Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | TYR | P14679 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764553 | 0.83 | HPGD (0.54) | TYRESR2NPC1PTPN1KDM4E | |
| SCHEMBL5656903 | 0.74 | USP2 (0.52) | PTGS1TYRPTGS2PDE4BPDE4D | |
| SCHEMBL28142014 | 0.73 | PTGS1 (1.00) | PTGS1TYRPTGS2PDE4BPDE4D | |
| Moracin M SCHEMBL29979946 | 0.72 | PDE4D (1.00) | PTGS1TYRPTGS2PDE4BPDE4D | |
| Moracin M SCHEMBL1740981 | 0.72 | PDE4D (1.00) | PTGS1TYRPTGS2PDE4BPDE4D | |
| SCHEMBL2166723 | 0.71 | ESR2 (1.00) | PTGS1ESR2MIFNPC1KDM4E | |
| SCHEMBL9809597 | 0.70 | MAOB (0.47) | MIFKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL308343 | 0.70 | SHBG (0.67) | PTGS1TYRPTGS2PDE4BPDE4D | |
| SCHEMBL5296804 | 0.69 | HSD17B3 (0.68) | PTGS1TYRESR2MIFNPC1 | |
| SCHEMBL9138143 | 0.69 | SHBG (1.00) | PTGS1TYRPTGS2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620918-B1 | CARBON DIOXIDE DETECTOR | JOHNSON & JOHNSON PROFESSIONAL (GB) | 1997-07-30 | — | — | EP | claimed |
| EP-0448923-B1 | Method and apparatus for detecting biological activities in a specimen | AVL PHOTRONICS CORP (US) | 1996-01-03 | — | — | EP | claimed |
| EP-0105870-B1 | MEASUREMENT DEVICE FOR DETERMINING THE CARBON DIOXIDE CONTENT OF A SAMPLE | AVL AG (CH) | 1987-02-11 | — | — | EP | disclosed |
| EP-0105870-A2 | Measurement device for determining the carbon dioxide content of a sample | AVL AG (CH) | 1984-04-18 | — | — | EP | disclosed |