Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28426151 | 0.98 | GAA (0.52) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL391332 | 0.91 | GAA (0.65) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28234269 | 0.88 | GAA (0.62) | GAAMGAMSIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27917473 | 0.88 | GAA (0.62) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1838345 | 0.86 | — | — | |
| SCHEMBL6139899 | 0.85 | ALDH1A1 (0.54) | GAAMGAMSIMGAM2EGLN1 | |
| Water SCHEMBL262185 | 0.84 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6139898 | 0.84 | ALDH1A1 (0.53) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL6671889 | 0.83 | CA1 (0.46) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL20188850 | 0.83 | ALDH1A1 (0.42) | GAAMGAMSIMGAM2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207465-B | Heterocyclic compounds and their use | 财团法人卫生研究院 | 2021-09-10 | — | — | CN | disclosed |
| EP-3197885-B1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RES INST (TW) | 2020-11-18 | — | — | EP | disclosed |
| CN-111454190-A | Method for synthesizing oxiracetam by adopting NaA type molecular membrane reactor | 中海油天津化工研究设计院有限公司 | 2020-07-28 | — | — | CN | disclosed |
| US-20190048344-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | ALNYLAM PHARMACEUTICALS INC (US) | 2019-02-14 | — | — | US | disclosed |
| US-9926298-B2 | Heterocyclic compounds and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2018-03-27 | — | — | US | disclosed |
| US-20180009786-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RES INST (TW) | 2018-01-11 | — | — | US | disclosed |
| US-9862703-B2 | Heterocyclic compounds and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2018-01-09 | — | — | US | disclosed |
| EP-3197885-A2 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | Chao, Yu-Sheng (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048861-A2 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2016-03-31 | — | — | WO | disclosed |
| US-20160083369-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NAT HEALTH RESEARCH INSTITUTES (TW) | 2016-03-24 | — | — | US | disclosed |
| US-4827014-A | BUILDERS, STABILIZERS, COMPLEXING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| US-4732887-A | RESIN IN VOIDS FOR CHROMATOGRAPHY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-03-22 | — | — | US | disclosed |
| US-4686296-A | Process for producing oxiracetam | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0223328-A1 | Process for producing oxiracetam | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-05-27 | — | — | EP | disclosed |
| US-4599175-A | CHELATING RESIN | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-07-08 | — | — | US | disclosed |
| US-4421693-A | INSECTICIDES, MITICIDES OR NEMATOCIDES | OTSUKA CHEMICAL CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4413005-A | 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1983-11-01 | — | — | US | disclosed |
| US-4405418-A | PURIFICATION OF SODIUM CHLORIDE ELECTROLYTE WITH CHELATING ION EXCHANGE RESIN OF CROSSLINKED CHLOROMETHYLSTYRENE-DIVINYLBENZENE COPOLYMER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-09-20 | — | — | US | disclosed |
| US-4358546-A | Spherical porous cross-linked copolymers of chloromethylstyrene and divinylbenzene and the derivative thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-11-09 | — | — | US | disclosed |
| US-4118396-A | PYRROLIDIN-2-ONES, CNS AGENTS | I.S.F. S.P.A. (IT) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009786-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | CXCL12, HPGDS, MCL1 | GAA 3244/4885MGAM 4534/4885SI 2603/4885 |
| US-20190048344-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | DNMT1, LCK, MCTS1 | GAA 2358/4885MGAM 1620/4885SI 1996/4885 |
| US-20160083369-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | CXCL12, HPGDS, MCL1 | GAA 3244/4885MGAM 4534/4885SI 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.