Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL386933 | 0.80 | S1PR1 (0.38) | S1PR1S1PR3S1PR5 | |
| SCHEMBL387022 | 0.74 | GRM5 (0.37) | S1PR1S1PR3S1PR5 | |
| SCHEMBL385736 | 0.73 | ALOX5 (0.36) | S1PR1S1PR3S1PR5 | |
| Oxalic Acid SCHEMBL5657249 | 0.70 | S1PR1 (0.41) | S1PR1S1PR3S1PR5 | |
| SCHEMBL385597 | 0.69 | S1PR1 (0.38) | S1PR1S1PR3S1PR5 | |
| SCHEMBL5661079 | 0.69 | S1PR1 (0.38) | S1PR1S1PR3S1PR5 | |
| SCHEMBL387331 | 0.69 | TRPV3 (0.33) | — | |
| SCHEMBL5658606 | 0.69 | RAB9A (0.32) | S1PR1S1PR3S1PR5 | |
| SCHEMBL385735 | 0.69 | RAB9A (0.32) | S1PR1S1PR3S1PR5 | |
| Oxalic Acid SCHEMBL5658166 | 0.69 | S1PR1 (0.41) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199150-B2 | Amino alcohol compounds | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20050043386-A1 | Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these | SANKYO COMPANY, LIMITED (JP) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043386-A1 | Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these | PHOSPHO1, CD4, FCGRT | S1PR1 257/4885S1PR3 414/4885S1PR5 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.