Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPD | P32754 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | DTYMK | P23919 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534229 | 0.80 | POLB (0.57) | TSHRPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL4904 | 0.80 | POLB (0.57) | TSHRPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL1043222 | 0.80 | POLB (0.57) | TSHRPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL4449468 | 0.78 | POLB (0.46) | POLBMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL5303474 | 0.74 | ALDH1A1 (0.48) | POLBALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL14067636 | 0.74 | ALDH1A1 (0.40) | POLBMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL617411 | 0.74 | KMT2A (0.48) | MEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL24371870 | 0.74 | SMN1; SMN2 (0.48) | TSHRPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL29599533 | 0.74 | SMN1; SMN2 (0.48) | TSHRPOLBMAPTMEN1ALDH1A1 | |
| SCHEMBL29599304 | 0.74 | SMN1; SMN2 (0.48) | TSHRPOLBMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060047105-A1 | Polymer-supported reagent for the preparation of disulfide-bridged peptides | PEPTIDES INTERNATIONAL, INC. | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047105-A1 | Polymer-supported reagent for the preparation of disulfide-bridged peptides | GPX4, P4HB, GFER | TSHR 1701/4885POLB 1748/4885MAPT 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.