Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KAT7 | O95251 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654171 | 0.79 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8KAT7 | |
| SCHEMBL29520183 | 0.75 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4659266 | 0.74 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL8560391 | 0.73 | TDP1 (0.40) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL23320075 | 0.69 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL970863 | 0.69 | HPGD (0.31) | MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL27785439 | 0.69 | KAT7 (0.37) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL7915450 | 0.68 | CYP2D6 (0.56) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2648013 | 0.68 | ADORA3 (0.46) | MEN1KMT2AALDH1A1PIK3CDPIK3CG | |
| SCHEMBL9096607 | 0.67 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084170-B2 | Thiophene-amd thiazolesulfonamides as antineoplastic agents | ELI LILLY AND COMPANY (US) | 2006-08-01 | — | — | US | disclosed |