Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 11/20 | 0.58 |
| ▸ | CA1 | P00915 | 10/20 | 0.58 |
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | CA12 | O43570 | 5/20 | 0.58 |
| ▸ | LTA4H | P09960 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MMP14 | P50281 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP16 | P51512 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662142 | 0.91 | LTA4H (0.70) | POLBMEN1KMT2ACA2CA1 | |
| SCHEMBL5661814 | 0.87 | LTA4H (0.62) | LTA4HRECQLKDM4E | |
| SCHEMBL5659647 | 0.87 | LTA4H (0.62) | LTA4HRECQLKDM4E | |
| SCHEMBL5659377 | 0.86 | LTA4H (0.63) | LTA4HRECQLKDM4E | |
| SCHEMBL5659737 | 0.85 | LTA4H (0.62) | POLBMEN1KMT2ALTA4HRECQL | |
| SCHEMBL5661530 | 0.84 | LTA4H (0.61) | MEN1KMT2ALTA4HRECQLKDM4E | |
| SCHEMBL5660688 | 0.84 | LTA4H (0.60) | LTA4HRECQLKDM4E | |
| SCHEMBL22069565 | 0.83 | RECQL (0.75) | MEN1KMT2ALTA4HRECQLKDM4E | |
| SCHEMBL22069745 | 0.81 | RECQL (0.71) | MEN1KMT2ALTA4HRECQLMMP2 | |
| SCHEMBL5659837 | 0.80 | RECQL (0.58) | POLBLTA4HRECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | TAAR1 1227/4885POLB 1455/4885MEN1 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.