Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.74 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661973 | 0.86 | CA2 (1.00) | CA2CAMK2AFNTAFNTBESR1 | |
| Trifluoroacetic Acid SCHEMBL5657716 | 0.85 | CA2 (0.52) | CA2CTBP2CES1 | |
| Trifluoroacetic Acid SCHEMBL5892868 | 0.85 | CES1 (0.62) | CA2CES1 | |
| Water SCHEMBL28074006 | 0.84 | CA2 (0.95) | CA2CAMK2AFNTAFNTBESR1 | |
| Trifluoroacetic Acid SCHEMBL5659578 | 0.84 | CA2 (0.50) | CA2CTBP2CES1 | |
| Trifluoroacetic Acid SCHEMBL26098787 | 0.84 | CA2 (0.50) | CA2 | |
| Trifluoroacetic Acid SCHEMBL5659772 | 0.84 | CA2 (0.50) | CA2CES1 | |
| Trifluoroacetic Acid SCHEMBL5655817 | 0.80 | HTT (0.51) | CTBP2 | |
| Trifluoroacetic Acid SCHEMBL5657379 | 0.80 | CTBP2 (0.50) | CA2BLMCTBP2CES1 | |
| Hydroquinone SCHEMBL27638163 | 0.79 | CA2 (0.50) | CA2CAMK2AESR1ESR2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |