Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512650 | 0.87 | CA2 (0.64) | CA2MEN1KMT2ASMN1; SMN2 | |
| Methane SCHEMBL27547221 | 0.85 | CA2 (0.61) | CA2MEN1KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5657716 | 0.84 | CA2 (0.52) | CA2KMT2ACES1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5657680 | 0.84 | CA2 (0.74) | CA2CES1 | |
| Trifluoroacetic Acid SCHEMBL5892868 | 0.83 | CES1 (0.62) | CA2MEN1KMT2ACES1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5659578 | 0.82 | CA2 (0.50) | CA2CES1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL26098787 | 0.82 | CA2 (0.50) | CA2 | |
| Trifluoroacetic Acid SCHEMBL5657671 | 0.80 | EGFR (0.46) | CES1 | |
| Trifluoroacetic Acid SCHEMBL5655817 | 0.78 | HTT (0.51) | — | |
| SCHEMBL28268026 | 0.77 | CES1 (0.64) | MEN1KMT2ACES1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |