Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29794541 | 0.88 | CA2 (0.59) | CA2CTBP2GAAALDH1A1RAB9A | |
| SCHEMBL328637 | 0.88 | CA2 (0.64) | CA2CTBP2GAASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5795470 | 0.86 | CA2 (0.61) | CA2CTBP2GAASMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL5657680 | 0.85 | CA2 (0.74) | CA2CTBP2CES1 | |
| Trifluoroacetic Acid SCHEMBL5892868 | 0.85 | CES1 (0.62) | CA2CES1SMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL5659772 | 0.84 | CA2 (0.50) | CA2CES1SMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL5659578 | 0.84 | CA2 (0.50) | CA2CTBP2CES1RAB9A | |
| Trifluoroacetic Acid SCHEMBL26098787 | 0.84 | CA2 (0.50) | CA2 | |
| SCHEMBL13106182 | 0.82 | CA2 (0.57) | CA2CTBP2GAASMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL28713743 | 0.81 | LOXL2 (0.64) | CTBP2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-5663297-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-09-02 | — | — | US | disclosed |