Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95949 | 0.86 | MAOB (0.50) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14813932 | 0.85 | TSHR (0.44) | TSHRMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL27795621 | 0.84 | TDP1 (0.46) | TSHRHDAC6L3MBTL1HTR1AADRA1D | |
| SCHEMBL27795617 | 0.84 | TSHR (0.42) | TSHRL3MBTL1HTR1AADRA1DADRA1A | |
| SCHEMBL3158759 | 0.84 | TSHR (0.64) | TSHRMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL27816607 | 0.83 | L3MBTL1 (0.48) | TSHRHDAC6L3MBTL1HTR1AADRA1D | |
| SCHEMBL7007175 | 0.80 | MAOB (0.45) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27810352 | 0.80 | MAOB (0.51) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8751709 | 0.80 | TSHR (0.64) | TSHRMAOBLMNACYP1A2PTGS1 | |
| SCHEMBL919605 | 0.79 | MAOB (0.50) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109233-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050234038-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-10-20 | — | — | US | disclosed |
| US-20040235883-A1 | Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders | ALTANA PHARMA AG (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234038-A1 | Protease inhibitors | SPINT2, CTRL, PRSS1 | TSHR 3822/4885MAOB 3137/4885LMNA 2415/4885 |
| US-20040235883-A1 | Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders | SLC10A2, ALPI, SI | TSHR 1562/4885MAOB 321/4885LMNA 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.