SCHEMBL565818

SCHEMBL565818

CC1(C)OCC(COCc2ccccc2)O1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 2/20 0.48
SIGMAR1 Q99720 2/20 0.48
LMNA P02545 1/20 0.47
CA2 P00918 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
TSHR P16473 1/20 0.41
HRH4 Q9H3N8 4/20 0.40
HRH3 Q9Y5N1 4/20 0.40
PTPN1 P18031 1/20 0.39
CDC25B P30305 1/20 0.39
F10 P00742 1/20 0.38
DRD1 P21728 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5606199 1.00 TMEM97 (0.48) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL2182755 1.00 TMEM97 (0.48) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL3508958 0.93 TMEM97 (0.45) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL25305166 0.92 TMEM97 (0.44) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL25303747 0.92 TMEM97 (0.44) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL24207804 0.92 TMEM97 (0.44) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL12882864 0.88 TMEM97 (0.42) TMEM97SIGMAR1LMNACA2TAAR1
SCHEMBL26510718 0.87 CA2 (0.43) TMEM97SIGMAR1LMNACA2TSHR
SCHEMBL11932962 0.86 CA1 (0.45) TMEM97SIGMAR1CA2TSHR
SCHEMBL14317554 0.86 CA1 (0.45) TMEM97SIGMAR1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108409782-B Synthetic method of alkynyl-modified phospholipid derivative for preparing functional phospholipid giant vesicle 咸阳师范学院 2020-05-15 CN claimed
CN-108409782-A A kind of synthetic method for the alkynyl-modified phospholipid derivative being used to prepare functional phosphatide Giant Vesicles 咸阳师范学院 2018-08-17 CN claimed
JP-6157506-A None JP disclosed
CN-122055141-A Polyvinylpyrrolidone stabilizer, composition, use and preparation method thereof 环球生命科学解决方案加拿大有限公司 2026-05-15 CN disclosed
US-12595336-B2 Method for producing maleimide polyethylene glycol derivative NOF CORPORATION (JP) 2026-04-07 US disclosed
US-12453785-B2 Macrocyclic chelators and methods of use thereof JANSSEN BIOTECH, INC. (US) 2025-10-28 US disclosed
EP-4265667-B1 METHOD FOR PRODUCING MALEIMIDE POLYETHYLENE GLYCOL DERIVATIVE NOF CORP (JP) 2025-07-23 EP disclosed
US-20250114305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF SANOFI (FR) 2025-04-10 US disclosed
WO-2025056466-A1 POLYVINYLPYRROLIDONE STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 WO disclosed
WO-2025056467-A1 POLYPHOSPHOESTER STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 WO disclosed
EP-4466248-A1 LIPIDIC COMPOUNDS, AND USES THEREOF Sanofi (FR) 2024-11-27 EP disclosed
US-6143908-A Process for preparation of 1,3-dioxolane-4-methanol compounds DAISO CO., LTD. (JP) 2000-11-07 US disclosed
US-6124479-A Process for the preparation of 1,3-dioxolane-4-methanols DAISO CO., LTD. (JP) 2000-09-26 US disclosed
EP-0930311-A1 PROCESS FOR PREPARING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS DAISO CO., LTD. (JP) 1999-07-21 EP disclosed
EP-0926147-A1 PROCESS FOR PREPARING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS DAISO CO., LTD. (JP) 1999-06-30 EP disclosed
US-5795561-A TUMOR SPECIFIC; MEDICAL DIAGNOSIS THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1998-08-18 US disclosed
US-5347030-A Radioiodinated phospholipid ether analogues and methods of using same THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1994-09-13 US disclosed
JP-H06157506-A PRODUCTION OF ISOPROPYLIDENEBENZYLGLYCEROL NIPPON OIL & FATS CO LTD 1994-06-03 JP disclosed
EP-0191724-A2 1,4-Dihydropyridine derivatives, their preparation and pharmaceutical compositions containing them SANDOZ AG (CH) 1986-08-20 EP disclosed
US-4423071-A ANOXIA, ANTICONVULSANTS, GLYCERYL BIS-(DI-N-PROPYLACETATES) SANOFI (FR) 1983-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595336-B2 Method for producing maleimide polyethylene glycol derivative F12, C9, H1-0 TMEM97 2643/4885SIGMAR1 675/4885LMNA 468/4885
US-20250114305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF NR1H2, NR1H3, LPAR3 TMEM97 856/4885SIGMAR1 40/4885LMNA 555/4885
US-12453785-B2 Macrocyclic chelators and methods of use thereof CLASP1, CLTC, CD47 TMEM97 2144/4885SIGMAR1 4517/4885LMNA 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.