SCHEMBL24207804

SCHEMBL24207804

CC1(C)OCC(COCCOCCOCCOCCOCc2ccccc2)O1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
CA2 P00918 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
LMNA P02545 1/20 0.40
NAAA Q02083 1/20 0.38
TSHR P16473 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HRH4 Q9H3N8 4/20 0.34
HRH3 Q9Y5N1 4/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPK14 Q16539 1/20 0.34
F10 P00742 1/20 0.34
PTPN1 P18031 1/20 0.34
CDC25B P30305 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25305166 1.00 TMEM97 (0.44) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL25303747 1.00 TMEM97 (0.44) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL3508958 0.99 TMEM97 (0.45) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL12882864 0.94 TMEM97 (0.42) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL5606199 0.92 TMEM97 (0.48) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL2182755 0.92 TMEM97 (0.48) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL565818 0.92 TMEM97 (0.48) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL878159 0.86 TMEM97 (0.46) TMEM97SIGMAR1CA2TAAR1LMNA
SCHEMBL28056762 0.86 SIGMAR1 (0.46) TMEM97SIGMAR1CA2MEN1KMT2A
SCHEMBL4191243 0.86 TMEM97 (0.46) TMEM97SIGMAR1CA2TAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF SANOFI (FR) 2025-04-10 US disclosed
EP-4466248-A1 LIPIDIC COMPOUNDS, AND USES THEREOF Sanofi (FR) 2024-11-27 EP disclosed
US-20230295097-A1 LIPIDIC COMPOUNDS COMPRISING AT LEAST ONE TERMINAL RADICAL OF FORMULA -NH-CX-A OR -NH-CX-NH-A, COMPOSITIONS CONTAINING THEM AND USES THEREOF SANOFI PASTEUR (FR) 2023-09-21 US disclosed
US-20230295097-A1 LIPIDIC COMPOUNDS COMPRISING AT LEAST ONE TERMINAL RADICAL OF FORMULA -NH-CX-A OR -NH-CX-NH-A, COMPOSITIONS CONTAINING THEM AND USES THEREOF SANOFI PASTEUR (FR) 2023-09-21 US disclosed
US-20230293447-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF SANOFI PASTEUR (FR) 2023-09-21 US disclosed
US-20230293447-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF SANOFI PASTEUR (FR) 2023-09-21 US disclosed
WO-2023135305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF SANOFI (FR) 2023-07-20 WO disclosed
EP-4182296-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF Sanofi Pasteur (FR) 2023-05-24 EP disclosed
EP-4182302-A1 LIPIDIC COMPOUNDS COMPRISING AT LEAST ONE TERMINAL RADICAL OF FORMULA -NH-CX-A OR -NH-CX-NH-A, COMPOSITIONS CONTAINING THEM AND USES THEREOF Sanofi Pasteur (FR) 2023-05-24 EP disclosed
WO-2022013443-A1 LIPIDIC COMPOUNDS COMPRISING AT LEAST ONE TERMINAL RADICAL OF FORMULA -NH-CX-A OR -NH-CX-NH-A, COMPOSITIONS CONTAINING THEM AND USES THEREOF SANOFI PASTEUR (FR) 2022-01-20 WO disclosed
WO-2022013439-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF SANOFI PASTEUR (FR) 2022-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293447-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF MTTP, CETP, LNPEP TMEM97 3302/4885SIGMAR1 1580/4885CA2 2229/4885
US-20230295097-A1 LIPIDIC COMPOUNDS COMPRISING AT LEAST ONE TERMINAL RADICAL OF FORMULA -NH-CX-A OR -NH-CX-NH-A, COMPOSITIONS CONTAINING THEM AND USES THEREOF PRDX5, ANXA5, PRDX1 TMEM97 2027/4885SIGMAR1 505/4885CA2 2326/4885
US-20250114305-A1 LIPIDIC COMPOUNDS, AND USES THEREOF NR1H2, NR1H3, LPAR3 TMEM97 856/4885SIGMAR1 40/4885CA2 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.