Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624601 | 0.97 | FAAH (0.32) | FAAHPHGDHMGLL | |
| Hydrogen Sulfide SCHEMBL28323707 | 0.82 | FAAH (0.35) | FAAHPHGDHMGLL | |
| SCHEMBL1829946 | 0.82 | — | — | |
| SCHEMBL726729 | 0.78 | MGLL (0.40) | PHGDHMGLL | |
| SCHEMBL2457046 | 0.78 | MGLL (0.40) | PHGDHMGLL | |
| SCHEMBL6926105 | 0.78 | MGLL (0.40) | PHGDHMGLL | |
| SCHEMBL42220 | 0.78 | MGLL (0.40) | PHGDHMGLL | |
| SCHEMBL3658220 | 0.78 | MGLL (0.40) | PHGDHMGLL | |
| SCHEMBL2807354 | 0.78 | MGLL (0.40) | PHGDHMGLL | |
| SCHEMBL3558104 | 0.78 | MGLL (0.40) | PHGDHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113557231-A | Novel 3- (2-bromo-4-alkynyl-6-alkoxyphenyl) -3-pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2021-10-26 | — | — | CN | claimed |
| US-20220142770-A1 | LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER | RXSIGHT, INC. | 2022-05-12 | — | — | US | disclosed |
| CN-108349888-B | Novel alkynyl-substituted 3-phenylpyrrolidine-2, 4-diones and their use as herbicides | 拜耳作物科学股份公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-113557232-A | Specific substituted 3- (2-alkoxy-6-alkyl-4-propynylphenyl) -3-pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113557231-A | Novel 3- (2-bromo-4-alkynyl-6-alkoxyphenyl) -3-pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113557230-A | Specific substituted 3- (2-halogen-6-alkyl-4-propynylphenyl) -3-pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2021-10-26 | — | — | CN | disclosed |
| WO-2021081013-A1 | LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER | RXSIGHT, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| US-20210113328-A1 | LIGHT ADJUSTABLE INTRAOCULAR LENS WITH A MODULABLE ABSORPTION FRONT PROTECTION LAYER | RXSIGHT, INC. (US) | 2021-04-22 | — | — | US | disclosed |
| CN-112334446-A | 2-bromo-6-alkoxyphenyl-substituted pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3211026-B1 | ON-DEMAND PHOTOINITIATED POLYMERIZATION | CALIFORNIA INST OF TECHN (US) | 2018-06-27 | — | — | EP | disclosed |
| US-20120035293-A1 | ON-DEMAND PHOTOINITIATED POLYMERIZATION | ENERGY, UNITED STATES DEPARTMENT OF | 2012-02-09 | — | — | US | disclosed |
| WO-2012006370-A2 | ON-DEMAND PHOTOINITIATED POLYMERIZATION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20110201657-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-18 | — | — | US | disclosed |
| US-20090275619-A1 | Amide Substituted Indazole and Benzotriazole Derivatives as Poly(ADP-Ribose)Polymerase (PARP) Inhibitors | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-11-05 | — | — | US | disclosed |
| EP-2007733-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007113596-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-10-11 | — | — | WO | disclosed |
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |
| WO-1999058475-A2 | PREPARATION OF COMPOUNDS USING POLYMER SUPPORTED REAGENTS | CAMBRIDGE COMBINATORIAL LIMITED (GB) | 1999-11-18 | — | — | WO | disclosed |
| CN-1045597-C | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1999-10-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275619-A1 | Amide Substituted Indazole and Benzotriazole Derivatives as Poly(ADP-Ribose)Polymerase (PARP) Inhibitors | PARP1, PARP3, PARP2 | FAAH 3406/4885PHGDH 2447/4885MGLL 4795/4885 |
| US-20110201657-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | PARP1, PARP3, PARP2 | FAAH 3406/4885PHGDH 2447/4885MGLL 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.