SCHEMBL5658371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27642761	0.76	PTGER2 (0.41)	ROCK1TRPV1RAB9ANR2F2MAPT
	SCHEMBL5431368	0.75	ROS1 (0.51)	ROCK1ALDH1A1TRPV1RAB9ANR2F2
	SCHEMBL27642766	0.73	TRPV1 (0.43)	ROCK1ALDH1A1KMT2ATRPV1MAPT
	SCHEMBL9253552	0.72	ALOX5 (0.52)	CYP11B1CYP11B2ALDH1A1HDAC1HDAC2
	SCHEMBL6625347	0.72	TRPV1 (0.53)	ROCK1TRPV1
	SCHEMBL5411314	0.72	TRPV1 (0.53)	TRPV1
	SCHEMBL5658073	0.72	TRPV1 (0.41)	ROCK1TRPV1RAB9ANR2F2HDAC6
	SCHEMBL6623343	0.72	CYP3A4 (0.40)	CYP11B1CYP11B2ROCK1ALDH1A1KMT2A
	SCHEMBL27663654	0.72	TRPV1 (0.40)	ROCK1TRPV1HDAC6
	SCHEMBL5658084	0.71	L3MBTL1 (0.39)	ROCK1ALDH1A1TRPV1RAB9ANR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.