Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660295 | 0.89 | MEN1 (0.58) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| SCHEMBL5659163 | 0.87 | KMT2A (0.58) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| SCHEMBL5660460 | 0.85 | KMT2A (0.65) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| SCHEMBL5660699 | 0.79 | MEN1 (0.58) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| SCHEMBL5660862 | 0.79 | MEN1 (0.55) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| SCHEMBL5659324 | 0.79 | KMT2A (0.63) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| SCHEMBL5661106 | 0.76 | MEN1 (0.54) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6366426 | 0.74 | MEN1 (0.52) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6370935 | 0.74 | MEN1 (0.53) | KMT2AMEN1CYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6365461 | 0.74 | MEN1 (0.51) | KMT2AMEN1CYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256194-B2 | Prevent thrombosis; anticholesterol agents; cardiovascular disorders; anticancer agents | MORPHOCHEM (DE) | 2007-08-14 | — | — | US | disclosed |
| EP-1370526-B1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | MORPHOCHEM AG KOMB CHEMIE (DE) | 2006-05-24 | — | — | EP | disclosed |
| US-20040082547-A1 | Novel compounds that inhibit factor xa activity | MORPHOCHEM (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1370526-A1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068390-A1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082547-A1 | Novel compounds that inhibit factor xa activity | F11, TFPI, SERPINC1 | KMT2A 3724/4885MEN1 625/4885CYP3A4 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.