Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | AANAT | Q16613 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659324 | 0.91 | KMT2A (0.63) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5660699 | 0.89 | MEN1 (0.58) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5660295 | 0.86 | MEN1 (0.58) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5660862 | 0.86 | MEN1 (0.55) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5662044 | 0.85 | MEN1 (0.56) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5661106 | 0.85 | MEN1 (0.54) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5658486 | 0.85 | KMT2A (0.57) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL5659163 | 0.85 | KMT2A (0.58) | KMT2AMEN1MAPTTSHRKDM4E | |
| Hydrochloric Acid SCHEMBL6370935 | 0.84 | MEN1 (0.53) | KMT2AMEN1MAPTTSHRKDM4E | |
| Hydrochloric Acid SCHEMBL6365463 | 0.83 | MEN1 (0.51) | KMT2AMEN1MAPTTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256194-B2 | Prevent thrombosis; anticholesterol agents; cardiovascular disorders; anticancer agents | MORPHOCHEM (DE) | 2007-08-14 | — | — | US | disclosed |
| EP-1370526-B1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | MORPHOCHEM AG KOMB CHEMIE (DE) | 2006-05-24 | — | — | EP | disclosed |
| US-20040082547-A1 | Novel compounds that inhibit factor xa activity | MORPHOCHEM (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1370526-A1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068390-A1 | DIAMIDES WHICH INHIBIT TRYPTASE AND FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082547-A1 | Novel compounds that inhibit factor xa activity | F11, TFPI, SERPINC1 | KMT2A 3724/4885MEN1 625/4885MAPT 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.