SCHEMBL5659311

SCHEMBL5659311

COC(=O)c1cc([Na])c(C(=O)O)c(C)c1S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.33
MAPT P10636 3/20 0.33
POLB P06746 2/20 0.33
NPC1 O15118 1/20 0.33
ABL1 P00519 1/20 0.33
PKM P14618 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
BCL2L1 Q07817 1/20 0.33
MCL1 Q07820 1/20 0.33
RIN1 Q13671 1/20 0.33
SAE1 Q9UBE0 1/20 0.33
UBA2 Q9UBT2 1/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
HPGD P15428 3/20 0.33
HSD17B10 Q99714 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31399261 0.80 L3MBTL1 (0.33) KDM4EMAPTPOLBNPC1ABL1
SCHEMBL471894 0.75 CA1 (0.39) KDM4EMAPTPOLBABL1KMT2A
SCHEMBL6415587 0.71 CA1 (0.46) KDM4EMAPTPOLBKMT2AHSD17B10
SCHEMBL271087 0.70 ALDH1A1 (0.41) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL4968176 0.70 CA1 (0.38) KDM4EMAPTPOLBABL1MEN1
SCHEMBL3283445 0.69 CDK1 (0.42) KDM4EMAPTKMT2AHPGDHSD17B10
SCHEMBL8604904 0.68 CA1 (0.42) KDM4EMAPTPOLBABL1KMT2A
SCHEMBL269782 0.68 ALDH1A1 (0.44) KDM4EPOLBMEN1KMT2AHPGD
SCHEMBL28456181 0.68 LCK (0.40) KDM4EMAPTPOLBNPC1ABL1
SCHEMBL10607482 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252219-B1 PROCESS FOR MAKING SULFONATED POLYESTER COMPOUNDS RHODIA (US) 2006-08-16 EP claimed
US-6576716-B1 Reacting sulfo salt-substituted aromatic carboxylic acid and alcohol; ester interchange or esterification with polyethylene terephthalate homo- or copolymer RHODIA, INC 2003-06-10 US claimed
EP-1252219-A2 PROCESS FOR MAKING SULFONATED POLYESTER COMPOUNDS RHODIA INC. (US) 2002-10-30 EP claimed
WO-2001040349-A2 PROCESS FOR MAKING SULFONATED POLYESTER COMPOUNDS RHODIA INC. (US) 2001-06-07 WO claimed
US-20180305859-A1 PATTERN COATED TEXTILE FOR ACTIVE COOLING MILLIKEN & COMPANY 2018-10-25 US disclosed
US-20180305860-A1 PATTERN COATED TEXTILE FOR ACTIVE COOLING MILLIKEN & COMPANY 2018-10-25 US disclosed
US-6576716-B1 Reacting sulfo salt-substituted aromatic carboxylic acid and alcohol; ester interchange or esterification with polyethylene terephthalate homo- or copolymer RHODIA, INC 2003-06-10 US disclosed