Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547987 | 1.00 | ALDH1A1 (0.45) | ALDH1A1THRBHPGDLMNAP2RX7 | |
| SCHEMBL5553317 | 0.88 | NPC1 (0.49) | ALDH1A1THRBHPGDP2RX7SMN1; SMN2 | |
| SCHEMBL5662123 | 0.88 | NPC1 (0.49) | ALDH1A1THRBHPGDP2RX7SMN1; SMN2 | |
| SCHEMBL5551391 | 0.82 | KMT2A (0.40) | HPGDLMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5661441 | 0.82 | KMT2A (0.40) | HPGDLMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5661449 | 0.82 | KMT2A (0.40) | HPGDLMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5551906 | 0.79 | MAPT (0.32) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5551867 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL5661594 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL5552059 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1THRBHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244153-A1 | Diamine Derivative, Process of Preparation Thereof, and Fungicide Comprising Diamine Derivative as an Active Ingredient | MITSUI CHEMICALS, INC. (JP) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244153-A1 | Diamine Derivative, Process of Preparation Thereof, and Fungicide Comprising Diamine Derivative as an Active Ingredient | DDT, AOC1, QDPR | ALDH1A1 327/4885THRB 3139/4885HPGD 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.