Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 17/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659679 | 1.00 | LTA4H (0.72) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5332157 | 0.93 | LTA4H (0.71) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5312399 | 0.88 | LTA4H (0.73) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5309904 | 0.86 | LTA4H (0.73) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5345072 | 0.86 | LTA4H (0.75) | LTA4HMEN1HPGDKMT2APOLB | |
| SCHEMBL5317908 | 0.84 | LTA4H (1.00) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5312794 | 0.81 | LTA4H (1.00) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5312966 | 0.81 | LTA4H (0.88) | LTA4H | |
| SCHEMBL5310104 | 0.80 | LTA4H (0.86) | LTA4HLMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL5310458 | 0.80 | LTA4H (1.00) | LTA4HPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | LTA4H 1/4885LMNA 1402/4885GAA 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.