Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11910172 | 0.87 | BIRC5 (0.60) | BIRC5ALDH1A1HPGDROCK2PIM1 | |
| SCHEMBL13183629 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDRAB9AKMT2AHSP90AA1 | |
| SCHEMBL13183573 | 0.86 | ROCK1 (0.48) | ALDH1A1HPGDROCK2PIM1PIM3 | |
| SCHEMBL5216431 | 0.85 | BIRC5 (0.55) | BIRC5ALDH1A1HPGDPRKD3PRKCG | |
| SCHEMBL5661388 | 0.80 | BIRC5 (0.46) | BIRC5ALDH1A1HPGDROCK2PIM1 | |
| Toluene SCHEMBL23051706 | 0.80 | BIRC5 (0.62) | BIRC5ALDH1A1HPGDPRKD3PRKCG | |
| SCHEMBL29733475 | 0.79 | BIRC5 (0.67) | BIRC5ALDH1A1PRKD3PRKCGPRKCB | |
| SCHEMBL4426563 | 0.79 | BIRC5 (0.67) | BIRC5ALDH1A1PRKD3PRKCGPRKCB | |
| SCHEMBL5662515 | 0.79 | FGFR1 (0.55) | BIRC5ALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL4265823 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDROCK2PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134923-A1 | ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20150065542-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2015-03-05 | — | — | US | disclosed |
| US-20140364617-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2014-12-11 | — | — | US | disclosed |
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MARZABADI MOHAMMAD R | 2007-02-22 | — | — | US | disclosed |
| US-7067534-B1 | Substituted anilinic piperidines as MCH selective antagonists | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| EP-1411942-A4 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | SYNAPTIC PHARMA CORP (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1411942-A1 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | Synaptic Pharmaceutical Corporation (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6727264-B1 | MELANIN CONCENTRATING HORMONE-1 RECEPTOR ANTAGONISTS; SLEEP, EATING, SEXUAL DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-27 | — | — | US | disclosed |
| WO-2003004027-A1 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MCHR1, MCHR2, MC1R | BIRC5 2851/4885ALDH1A1 620/4885HPGD 2602/4885 |
| US-20230134923-A1 | ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF | PIEZO1, VCL, VDAC3 | BIRC5 835/4885ALDH1A1 2385/4885HPGD 2664/4885 |
| US-20140364617-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | BIRC5 2618/4885ALDH1A1 1955/4885HPGD 3523/4885 |
| US-20150065542-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | BIRC5 2618/4885ALDH1A1 1955/4885HPGD 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.