Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688264 | 0.89 | AURKA (0.59) | FAAHMAPTAURKAJAK2ABL1 | |
| SCHEMBL828618 | 0.89 | AURKA (0.59) | FAAHMAPTAURKAJAK2ABL1 | |
| Hydrochloric Acid SCHEMBL2674335 | 0.87 | AURKA (0.58) | FAAHMAPTAURKAJAK2ABL1 | |
| Hydrochloric Acid SCHEMBL5008172 | 0.87 | AURKA (0.58) | FAAHMAPTAURKAJAK2ABL1 | |
| Trifluoroacetic Acid SCHEMBL3717753 | 0.81 | ALDH1A1 (0.68) | ABL1CYP3A4CHRM1NPSR1RAB9A | |
| SCHEMBL28793290 | 0.79 | FAAH (0.47) | FAAHMAPTAURKAJAK2ABL1 | |
| Trifluoroacetic Acid SCHEMBL31621378 | 0.78 | SMN1; SMN2 (0.52) | MAPTCHRM1NPSR1LMNARAB9A | |
| Indole SCHEMBL2364137 | 0.78 | FAAH (0.54) | FAAHMAPTAURKAJAK2ABL1 | |
| Trifluoroacetic Acid SCHEMBL8515314 | 0.77 | CHRM1 (0.48) | CYP3A4CHRM1NPSR1LMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL8515964 | 0.77 | SMN1; SMN2 (0.58) | MAPTCHRM1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |