Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | TXN | P10599 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792726 | 0.83 | BCHE (0.68) | SMN1; SMN2KMT2APOLBNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL31621378 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2APOLBNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3717753 | 0.79 | ALDH1A1 (0.68) | SMN1; SMN2KMT2ANPC1RAB9AKDM4E | |
| Trifluoroacetic Acid SCHEMBL6367442 | 0.78 | KMT2A (0.43) | SMN1; SMN2KMT2APOLBNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL8515314 | 0.78 | CHRM1 (0.48) | SMN1; SMN2KMT2ANPC1RAB9AKDM4E | |
| Trifluoroacetic Acid SCHEMBL5659985 | 0.77 | FAAH (0.49) | SMN1; SMN2RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL3184134 | 0.77 | KMT2A (0.64) | SMN1; SMN2KMT2APOLBNPC1RAB9A | |
| SCHEMBL30831170 | 0.76 | BCHE (0.59) | SMN1; SMN2KMT2APOLBNPC1RAB9A | |
| SCHEMBL1879820 | 0.76 | BCHE (0.59) | SMN1; SMN2KMT2APOLBNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL8362809 | 0.75 | KDM4E (0.45) | SMN1; SMN2KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |