Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | LTA4H | P09960 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | RNF4 | P78317 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664370 | 0.96 | KDM4E (0.69) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5661882 | 0.95 | KDM4E (0.67) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5660273 | 0.95 | KDM4E (0.67) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5661261 | 0.92 | KDM4E (0.77) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL22069671 | 0.86 | GAA (0.73) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5661438 | 0.85 | KDM4E (0.70) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5662163 | 0.84 | KDM4E (0.54) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5661992 | 0.84 | LTA4H (0.63) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 | |
| SCHEMBL5661162 | 0.83 | LTA4H (0.73) | LTA4HSMN1; SMN2RNF4HDAC3HDAC4 | |
| SCHEMBL5659423 | 0.83 | LTA4H (0.65) | KDM4ELTA4HSMN1; SMN2RECQLRNF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | KDM4E 1019/4885LTA4H 1/4885SMN1; SMN2 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.