Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443725 | 0.86 | TSHR (0.57) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL10040038 | 0.84 | TSHR (0.55) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL9303775 | 0.80 | TSHR (0.63) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL2209561 | 0.79 | CA1 (0.50) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL563245 | 0.78 | TSHR (0.60) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL563798 | 0.78 | TSHR (0.60) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL7175787 | 0.76 | TSHR (0.75) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL29272509 | 0.76 | TPMT (0.46) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL11416580 | 0.76 | TSHR (0.86) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL1403607 | 0.76 | TSHR (0.86) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011633-A1 | ANTAGONIST OF MAS-RELATED G PROTEIN-COUPLED RECEPTOR X2 AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2025-01-16 | — | — | WO | disclosed |
| US-20080194793-A1 | POLYTRIMETHYLENE TEREPHTHALATE HAVING A LOW LEVEL OF ACROLEIN AND A PROCESS FOR PRODUCING THE SAME | KELSEY DONALD ROSS | 2008-08-14 | — | — | US | disclosed |
| US-7381787-B2 | Polytrimethylene terephthalate having a low level of acrolein and a process for producing the same | SHELL OIL COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| US-7132427-B2 | Quinazolines and uses thereof | ARIAD PHARMACEUTICALS, INC. (US) | 2006-11-07 | — | — | US | disclosed |
| EP-1463742-A4 | NOVEL PYRAZOLO-AND PYRROLO-PYRIMIDINES AND USES THEREOF | ARIAD PHARMA INC (US) | 2006-05-10 | — | — | EP | disclosed |
| EP-1412367-A4 | NOVEL QUINOLINES AND USES THEREOF | ARIAD PHARMA INC (US) | 2006-05-03 | — | — | EP | disclosed |
| US-7019139-B2 | Quinolinones and uses thereof | ARIAD PHARMACEUTICALS, INC. (US) | 2006-03-28 | — | — | US | disclosed |
| EP-1408985-A4 | NOVEL PYRIDOPYRIMIDONES AND USES THEREOF | ARIAD PHARMA INC (US) | 2006-03-22 | — | — | EP | disclosed |
| US-7009054-B2 | Quinolines and uses thereof | ARIAD PHARMACEUTICALS, INC. (US) | 2006-03-07 | — | — | US | disclosed |
| EP-1408971-A4 | NOVEL QUINOLINES AND USES THEREOF | ARIAD PHARMA INC (US) | 2006-01-25 | — | — | EP | disclosed |
| US-20030100572-A1 | Novel pyridopyrimidones and uses thereof | ARIAD PHARMACEUTICALS,INC. | 2003-05-29 | — | — | US | disclosed |
| US-20030100573-A1 | Novel quinazolines and uses thereof | ARIAD PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003000011-A2 | NOVEL PYRIDOPYRIMIDINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000251-A1 | NOVEL IDOLINONES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000187-A2 | NOVEL PYRAZOLO-AND PYRROLO-PYRIMIDINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000186-A2 | NOVEL PHENYLAMINO-PYRIMIDINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000705-A1 | NOVEL QUINOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000266-A1 | NOVEL QUINOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000188-A2 | NOVEL QUINAZOLINES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000270-A1 | NOVEL PYRIDOPYRIMIDONES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100572-A1 | Novel pyridopyrimidones and uses thereof | UQCRB, RRM2B, CYP2B6 | TSHR 1337/4885TP53 2808/4885ALDH1A1 544/4885 |
| US-20030100573-A1 | Novel quinazolines and uses thereof | UQCRB, NQO2, RAB7A | TSHR 2143/4885TP53 3572/4885ALDH1A1 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.