Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918492 | 0.87 | RIPK1 (0.46) | RIPK1TAAR1AOC3TRPA1 | |
| SCHEMBL20087334 | 0.84 | RIPK1 (0.45) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL28133086 | 0.82 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL21322418 | 0.82 | TAAR1 (0.56) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL2418232 | 0.82 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL20427677 | 0.82 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL21688445 | 0.80 | TAAR1 (0.54) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL1019329 | 0.80 | RIPK1 (0.52) | RIPK1TAAR1AOC3TRPA1HRH1 | |
| SCHEMBL5079703 | 0.80 | HRH1 (0.52) | RIPK1TAAR1HRH1CACNA1FCHRM2 | |
| SCHEMBL25039225 | 0.80 | NPC1 (0.47) | RIPK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2016132247-A1 | FLUORO-ALCOHOL ADDITIVES FOR ORIENTATION CONTROL OF BLOCK COPOLYMERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-08-25 | — | — | WO | disclosed |
| EP-1461041-A4 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD (BB) | 2006-03-29 | — | — | EP | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| EP-1461041-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | Pharmasset Ltd. (BB) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003051298-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD. (BB) | 2003-06-26 | — | — | WO | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5180799-A | Organolithium-Organoaluminum Catalyst | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-19 | — | — | US | disclosed |
| EP-0434316-A1 | Processes | ZENECA LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |