SCHEMBL1019329

SCHEMBL1019329

CC(CC(C)(C)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.52
TAAR1 Q96RJ0 4/20 0.48
AOC3 Q16853 2/20 0.44
TRPA1 O75762 4/20 0.42
MAPK1 P28482 1/20 0.41
CACNA1F O60840 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
ADRA2B P18089 1/20 0.40
CHRM3 P20309 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
OPRK1 P41145 1/20 0.40
CACNA1D Q01668 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KCNH2 Q12809 1/20 0.40
CACNA1S Q13698 1/20 0.40
CACNA1C Q13936 1/20 0.40
SCN5A Q14524 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6265732 0.87 SLC6A2 (0.42) RIPK1TAAR1MAPK1SLC6A3ALDH1A1
SCHEMBL3001776 0.83 RIPK1 (0.49) RIPK1TAAR1AOC3TRPA1MAPK1
SCHEMBL6681969 0.80 TAAR1 (0.54) RIPK1TAAR1MAPK1ALDH1A1ALOX15
SCHEMBL5664123 0.80 RIPK1 (0.63) RIPK1TAAR1AOC3TRPA1CACNA1F
SCHEMBL10794218 0.78 TSHR (0.43) RIPK1
SCHEMBL29114549 0.78 TAAR1 (0.47) RIPK1TAAR1AOC3TRPA1SLC6A3
SCHEMBL839666 0.78 TAAR1 (0.47) RIPK1TAAR1MAPK1CACNA1FCHRM2
SCHEMBL18540489 0.78 TAAR1 (0.47) TAAR1MAPK1ALDH1A1ALOX15
SCHEMBL18567480 0.78 RIPK1 (0.50) RIPK1TAAR1AOC3TRPA1
SCHEMBL2418232 0.77 RIPK1 (0.53) RIPK1TAAR1AOC3TRPA1CACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450438-B2 High temperature polyethylene solution polymerization process DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-05-28 US claimed
US-8252735-B2 Fluids having partially hydrogenated substituted styrene linear dimers and method of making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-08-28 US claimed
US-20100048434-A1 Fluids Having Partially Hydrogenated Substituted Styrene Linear Dimers and Method of Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2010-02-25 US claimed
US-7629303-B2 good high pressure shear strength properties with good temperature-viscosity properties; synthesis of e.g. 2,4-bis-cyclohexyl-2-methylpentane, 2-phenyl-4-cyclohexyl-2-methylpentane and 2,4-diphenyl-2-methylpentane; transmission fluids for newer infinitely variable transmissions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-12-08 US claimed
EP-1778607-B1 FLUIDS HAVING PARTIALLY HYDROGENATED SUSBSTITUED STYRENE LINEAR DIMERS AND METHOD OF MAKING SAME EXXONMOBIL CHEM PATENTS INC (US) 2008-07-02 EP claimed
EP-1778607-A1 FLUIDS HAVING PARTIALLY HYDROGENATED SUSBSTITUED STYRENE LINEAR DIMERS AND METHOD OF MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2007-05-02 EP claimed
US-7193093-B2 Process for producing alkylene oxide SHELL OIL COMPANY (US) 2007-03-20 US claimed
US-7189886-B2 Process for producing alkylbenzene SHELL OIL COMPANY (US) 2007-03-13 US claimed
US-20060189836-A9 Process for producing alkylbenzene MURRAY BRENDAN D 2006-08-24 US claimed
EP-1644304-A2 PROCESS FOR PRODUCING ALKYLBENZENE SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-04-12 EP claimed
US-20060069212-A1 Fluids having partially hydrogenated substituted styrene linear dimers and method of making same EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-30 US claimed
WO-2006023572-A1 FLUIDS HAVING PARTIALLY HYDROGENATED SUSBSTITUED STYRENE LINEAR DIMERS AND METHOD OF MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-03-02 WO claimed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050054890-A1 Process for producing alkylbenzene MURRAY BRENDAN DERMOT (US) 2005-03-10 US claimed
US-20050020840-A1 Process for producing alkylene oxide SHELL OIL COMPANY 2005-01-27 US claimed
WO-2005005350-A2 PROCESS FOR PRODUCING ALKYLBENZENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-01-20 WO claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-6306223-B1 DEGREASING SURFACE OF ARTICLE WITH A SURFACTANT-FREE SOLVENT MIXTURE COMPRISING DIALKYL ESTER OF ALIPHATIC DIACID AND COMPOUND MISCIBLE IN DIESTER AND DISSOLVING FATTY COMPOUNDS CONTAMINATING ARTICLE, REPEATING PROCEDURE RHODIA CHIMIE (FR) 2001-10-23 US claimed
US-5773398-A Cleaning composition based on an aliphatic hydrocarbon compound comprising at least two aromatic substituents RHONE-POULENC CHIMIE (FR) 1998-06-30 US claimed
JP-8085254-A None JP disclosed
JP-8109397-A None JP disclosed
JP-9176665-A None JP disclosed
JP-9227888-A None JP disclosed
CN-108350389-B Lubricating grease for elevator sling, and traction elevator 株式会社日立制作所 2021-06-15 CN disclosed
CN-106398810-B The maintenance method of elevator cable lubricating grease, elevator cable, traction elevator and traction elevator 株式会社日立制作所 2019-08-13 CN disclosed
CN-108350389-A Lubricating grease for elevator sling, and traction elevator 株式会社日立制作所 2018-07-31 CN disclosed
US-9908963-B2 Particles for electrophoretic displays MERECK PATENT GMBH (DE) 2018-03-06 US disclosed
CN-105293254-B Lift appliance cable wire and the lift appliance using the cable wire 株式会社日立制作所 2018-02-09 CN disclosed
CN-106398810-A Grease for elevator rope, elevator rope, traction type elevator and maintenance method for traction type elevator 株式会社日立制作所 2017-02-15 CN disclosed
US-20160060379-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2016-03-03 US disclosed
CN-105293254-A Steel rope for elevator device and elevator using the same HITACHI LTD 2016-02-03 CN disclosed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
CN-103877703-A Dual-Core Comprising Zero Gradient Center And Positive Gradient Outer Core Layer ACUSHNET CO 2014-06-25 CN disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-8405301-B2 Organic electroluminescence element, display device and lighting device KONICA MINOLTA HOLDINGS INC. (JP) 2013-03-26 US disclosed
US-8318967-B2 Polysilane-supported transition metal catalyst for liquid phase reaction JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-11-27 US disclosed
EP-1726577-B1 METHOD OF CATALYTIC REACTION USING MICRO-REACTOR JAPAN SCIENCE & TECH AGENCY (JP) 2012-11-14 EP disclosed
EP-2498263-A1 Low and middle voltage electric cable Nexans (FR) 2012-09-12 EP disclosed
EP-2498262-A1 High or middle tension electric cable Nexans (FR) 2012-09-12 EP disclosed
US-8252735-B2 Fluids having partially hydrogenated substituted styrene linear dimers and method of making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-08-28 US disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20110095278-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-04-28 US disclosed
US-7888859-B2 Organic electroluminescence element, display device and lighting device KONICA MINOLTA HOLDINGS INC. (JP) 2011-02-15 US disclosed
EP-2271219-A1 USE OF DITHIIN TETRACARBOXIMIDES FOR TREATING PHYTOPATHOGENIC FUNGI Bayer CropScience AG (DE) 2011-01-12 EP disclosed
US-7820764-B2 Process for controlling the molecular weight of polymers of bromostyrene CHEMTURA CORPORATION (US) 2010-10-26 US disclosed
EP-1654242-B1 PROCESS FOR PRODUCING ALKYLENE OXIDE SHELL INT RESEARCH (NL) 2010-09-08 EP disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20100120990-A1 PROCESS FOR CONTROLLING THE MOLECULAR WEIGHT OF POLYMERS OF BROMOSTYRENE CHEMTURA CORPORATION (US) 2010-05-13 US disclosed
WO-2010043319-A1 USE OF DITHIIN TETRACARBOXIMIDES FOR TREATING PHYTOPATHOGENIC FUNGI BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-04-22 WO disclosed
US-7691954-B2 Process for controlling the molecular weight of polymers of bromostyrenes CHEMTURA CORPORATION (US) 2010-04-06 US disclosed
US-20100048434-A1 Fluids Having Partially Hydrogenated Substituted Styrene Linear Dimers and Method of Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2010-02-25 US disclosed
US-7663008-B2 Method of catalytic reaction using micro-reactor JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-02-16 US disclosed
US-7629303-B2 good high pressure shear strength properties with good temperature-viscosity properties; synthesis of e.g. 2,4-bis-cyclohexyl-2-methylpentane, 2-phenyl-4-cyclohexyl-2-methylpentane and 2,4-diphenyl-2-methylpentane; transmission fluids for newer infinitely variable transmissions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-12-08 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
US-20090143607-A1 Polysilane-Supported Transition Metal Catalyst JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-06-04 US disclosed
US-20090021147-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-22 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-1987880-A1 POLYSILANE-SUPPORTED TRANSITION METAL CATALYST Japan Science and Technology Agency (JP) 2008-11-05 EP disclosed
EP-1778607-B1 FLUIDS HAVING PARTIALLY HYDROGENATED SUSBSTITUED STYRENE LINEAR DIMERS AND METHOD OF MAKING SAME EXXONMOBIL CHEM PATENTS INC (US) 2008-07-02 EP disclosed
US-7358411-B2 Hydrocracking of diphenylalkanes SHELL OIL COMPANY (US) 2008-04-15 US disclosed
US-20070161834-A1 Method of catalytic reaction using micro-reactor JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-07-12 US disclosed
US-7217743-B2 Curable white ink KONICA CORPORATION (JP) 2007-05-15 US disclosed
EP-1778607-A1 FLUIDS HAVING PARTIALLY HYDROGENATED SUSBSTITUED STYRENE LINEAR DIMERS AND METHOD OF MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2007-05-02 EP disclosed
US-7193093-B2 Process for producing alkylene oxide SHELL OIL COMPANY (US) 2007-03-20 US disclosed
US-7189886-B2 Process for producing alkylbenzene SHELL OIL COMPANY (US) 2007-03-13 US disclosed
EP-1726577-A1 METHOD OF CATALYTIC REACTION USING MICRO-REACTOR Japan Science and Technology Agency (JP) 2006-11-29 EP disclosed
US-20060189836-A9 Process for producing alkylbenzene MURRAY BRENDAN D 2006-08-24 US disclosed
EP-1654242-A2 PROCESS FOR PRODUCING ALKYLENE OXIDE Shell Internationale Research Maatschappij B.V. (NL) 2006-05-10 EP disclosed
EP-1648847-A2 HYDROCRACKING OF DIPHENYLALKANES Shell Internationale Research Maatschappij B.V. (NL) 2006-04-26 EP disclosed
EP-1644304-A2 PROCESS FOR PRODUCING ALKYLBENZENE SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-04-12 EP disclosed
US-20060069212-A1 Fluids having partially hydrogenated substituted styrene linear dimers and method of making same EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-30 US disclosed
WO-2006023572-A1 FLUIDS HAVING PARTIALLY HYDROGENATED SUSBSTITUED STYRENE LINEAR DIMERS AND METHOD OF MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-03-02 WO disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050054890-A1 Process for producing alkylbenzene MURRAY BRENDAN DERMOT (US) 2005-03-10 US disclosed
US-20050049446-A1 Hydrocracking of diphenylalkanes SHELL OIL COMPANY 2005-03-03 US disclosed
US-20050020840-A1 Process for producing alkylene oxide SHELL OIL COMPANY 2005-01-27 US disclosed
WO-2005005351-A2 HYDROCRAKING OF DIPHENYLALKANES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-01-20 WO disclosed
WO-2005005350-A2 PROCESS FOR PRODUCING ALKYLBENZENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-01-20 WO disclosed
WO-2005005402-A2 PROCESS FOR PRODUCING ALKYLENE OXIDE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-01-20 WO disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20040019128-A1 Curable white ink KONICA CORPORATION (JP) 2004-01-29 US disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
EP-0674325-B1 Electrically insulating polymer composition and wire or cable using the same NIPPON PETROCHEMICALS CO LTD (JP) 2003-11-05 EP disclosed
EP-1273439-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-01-08 EP disclosed
US-6306223-B1 DEGREASING SURFACE OF ARTICLE WITH A SURFACTANT-FREE SOLVENT MIXTURE COMPRISING DIALKYL ESTER OF ALIPHATIC DIACID AND COMPOUND MISCIBLE IN DIESTER AND DISSOLVING FATTY COMPOUNDS CONTAMINATING ARTICLE, REPEATING PROCEDURE RHODIA CHIMIE (FR) 2001-10-23 US disclosed
EP-0972633-A1 Multilayer products comprising silicone compounds and a process for their production COMMER S.p.A. (IT) 2000-01-19 EP disclosed
US-5916860-A Cleaning and/or stripping composition, based on a dibasic acid ester and an ether RHONE-POULENC CHIMIE (FR) 1999-06-29 US disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5773398-A Cleaning composition based on an aliphatic hydrocarbon compound comprising at least two aromatic substituents RHONE-POULENC CHIMIE (FR) 1998-06-30 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
JP-H09227888-A FLUID FOR TRACTION DRIVE COSMO SOGO KENKYUSHO:KK 1997-09-02 JP disclosed
JP-H09176665-A TRACTION DRIVE FLUID COSMO SOGO KENKYUSHO:KK 1997-07-08 JP disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0281162-B1 Method for improving the electrical insulating characteristics of a fraction, electrical insulating substance, and electrical appliances containing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-06-12 EP disclosed
JP-H08109397-A DETERGENT AND CLEANING METHOD HITACHI CHEM CO LTD 1996-04-30 JP disclosed
JP-H0885254-A SOLVENT FOR PRESSURE SENSITIVE PHOTOCOPYING PAPER HITACHI CHEM CO LTD 1996-04-02 JP disclosed
US-5164467-A Low temperature curing PPG INDUSTRIES, INC. (US) 1992-11-17 US disclosed
WO-1992012965-A1 AZIRIDINE COMPOUNDS, ACRYLIC POLYMERS CONTAINING SAME AND COATING COMPOSITIONS CONTAINING SAID POLYMERS PPG INDUSTRIES, INC. (US) 1992-08-06 WO disclosed
US-5106993-A Nontoxic, coating compositions which harden at low temperature PPG INDUSTRIES INC. (US) 1992-04-21 US disclosed
US-4681980-A AROMATIC OLEFIN OIL NIPPON PETROCHEMICALS COMPANY LIMITED (JP) 1987-07-21 US disclosed
EP-0103868-B1 IMPROVED ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1987-04-08 EP disclosed
US-4493943-A MIXTURES OF DIARYLALKANES AND AROMATIC MONO-OR DI-OLEFINS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-01-15 US disclosed
EP-0115065-A2 Process for preparing oil-containing electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-08-08 EP disclosed
EP-0103868-A2 Improved electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-03-28 EP disclosed
EP-0103868-A2 Improved electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143607-A1 Polysilane-Supported Transition Metal Catalyst HPSE, SIK1, SIK2 RIPK1 1308/4885TAAR1 2077/4885AOC3 1479/4885
US-20050020840-A1 Process for producing alkylene oxide ADH1C, ADH1A, ADH5 RIPK1 2687/4885TAAR1 332/4885AOC3 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.