Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162583 | 0.82 | HIF1A (0.45) | HTR2ARIPK1ADRA2BADRA1AOPRK1 | |
| SCHEMBL5664123 | 0.80 | RIPK1 (0.63) | HRH1HTR2ARIPK1TDP1CACNA1F | |
| SCHEMBL5046280 | 0.80 | TAAR1 (0.48) | HRH1HTR2ARIPK1TDP1CACNA1F | |
| SCHEMBL416116 | 0.80 | RIPK1 (0.45) | HRH1HTR2ARIPK1TDP1CACNA1F | |
| SCHEMBL16291590 | 0.78 | SCN4A (0.45) | RIPK1 | |
| SCHEMBL5461547 | 0.78 | SCN4A (0.45) | RIPK1 | |
| SCHEMBL12435669 | 0.78 | RIPK1 (0.64) | RIPK1SLC6A3LMNAKDM4EMEN1 | |
| SCHEMBL11654729 | 0.78 | RIPK1 (0.45) | HRH1HTR2ARIPK1TDP1CACNA1F | |
| SCHEMBL5163930 | 0.78 | RIPK1 (0.64) | RIPK1SLC6A3LMNAKDM4EMEN1 | |
| SCHEMBL11691420 | 0.78 | RIPK1 (0.45) | HRH1HTR2ARIPK1TDP1CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004715-A2 | METHOD TO PREPARE BLOCK COPOLYMERS BY THE COMBINATION OF CATIONIC AND ANIONIC POLYMERIZATION | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2007117566-A2 | METHOD TO PREPARE BLOCK COPOLYMERS BY THE COMBINATION OF CATIONIC AND ANIONIC POLYMERIZATION | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2007-10-18 | — | — | WO | claimed |
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| CN-114606519-B | Olefin hydroalkylation reaction method based on electrochemical means and CuX catalysis | 天津理工大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
| CN-114606519-A | Olefin hydroalkylation reaction method based on electrochemical means and CuX catalysis | 天津理工大学 | 2022-06-10 | — | — | CN | disclosed |
| US-20210317114-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| EP-2004715-A2 | METHOD TO PREPARE BLOCK COPOLYMERS BY THE COMBINATION OF CATIONIC AND ANIONIC POLYMERIZATION | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007117566-A2 | METHOD TO PREPARE BLOCK COPOLYMERS BY THE COMBINATION OF CATIONIC AND ANIONIC POLYMERIZATION | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2007-10-18 | — | — | WO | disclosed |
| EP-0832158-B1 | GELS MADE FROM TRIBLOCK COPOLYMERS | RAYCHEM LTD (GB) | 1999-12-01 | — | — | EP | disclosed |
| US-5994446-A | METHACRYLATE-ALKYLENE(HYDROGENATED OR UNHYDROGENATED)-METHACRYLATE TRIBLOCK COPOLYMER HAVING NUMBER AVERAGE MOLECULAR WEIGHT MN OF AT LEAST 50,000 AND AT LEAST 200 PARTS BY WEIGHT OF EXTENDER LIQUID WEIGHT OF THE TRIBLOCK | RAYCHEM LIMITED (GB) | 1999-11-30 | — | — | US | disclosed |
| US-5180799-A | Organolithium-Organoaluminum Catalyst | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-19 | — | — | US | disclosed |
| EP-0434316-A1 | Processes | ZENECA LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | ALOX12, ALOX15B, ALOX5 | HRH1 1573/4885HTR2A 431/4885RIPK1 2240/4885 |
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | IL4, IL2, IL4I1 | HRH1 1930/4885HTR2A 4606/4885RIPK1 863/4885 |
| US-20210317114-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 | IL4, IL2, IL4I1 | HRH1 1930/4885HTR2A 4606/4885RIPK1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.