SCHEMBL5664801

SCHEMBL5664801

CCN(CC)c1ccc(C2CC(c3ccc(N(CC)CC)cc3)N=N2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
GFER P55789 3/20 0.45
MAPK1 P28482 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TSHR P16473 2/20 0.45
PSMD14 O00487 1/20 0.45
CYP3A4 P08684 1/20 0.45
RECQL P46063 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH3A1 P30838 1/20 0.42
ALDH1A3 P47895 1/20 0.42
RAB9A P51151 3/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
CNR2 P34972 2/20 0.41
MAPT P10636 3/20 0.40
NPC1 O15118 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10491473 0.81 MAPT (0.42) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL9061570 0.79 ALDH1A1 (0.40) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL12972037 0.77 KDM1A (0.54) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL5146728 0.74 ALDH1A1 (0.50) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL1735497 0.73 ALDH1A1 (0.74) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL11990258 0.72 ALDH1A1 (0.44) ALDH1A1GFERMAPK1L3MBTL1TSHR
Hydrochloric Acid SCHEMBL8046146 0.71 ALDH1A1 (0.70) ALDH1A1GFERMAPK1L3MBTL1TSHR
Hydrochloric Acid SCHEMBL8046149 0.71 ALDH1A1 (0.70) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL5146739 0.71 ALDH1A1 (0.48) ALDH1A1GFERMAPK1L3MBTL1TSHR
SCHEMBL5146741 0.71 RAB9A (0.50) ALDH1A1GFERMAPK1L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1247142-A4 ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS LEXMARK INT INC (US) 2006-06-07 EP disclosed
EP-1073935-A4 DUAL LAYER PHOTOCONDUCTORS WITH CHARGE GENERATION LAYER CONTAINING CHARGE TRANSPORT COMPOUND LEXMARK INT INC (US) 2004-10-27 EP disclosed
EP-1247142-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS Lexmark International, Inc. (US) 2002-10-09 EP disclosed
US-20020045115-A1 Charge generation layer for electrophotographic imaging member and a process for making thereof XEROX CORPORATION 2002-04-18 US disclosed
WO-2001092960-A1 PHOTOCONDUCTORS AND CHARGE GENERATION LAYERS COMPRISING POLYMERIC HINDERED PHENOLS LEXMARK INTERNATIONAL, INC. (US) 2001-12-06 WO disclosed
WO-2001051995-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS LEXMARK INTERNATIONAL, INC. (US) 2001-07-19 WO disclosed
EP-1073935-A1 DUAL LAYER PHOTOCONDUCTORS WITH CHARGE GENERATION LAYER CONTAINING CHARGE TRANSPORT COMPOUND Lexmark International, Inc. (US) 2001-02-07 EP disclosed
WO-1999056181-A1 DUAL LAYER PHOTOCONDUCTORS WITH CHARGE GENERATION LAYER CONTAINING CHARGE TRANSPORT COMPOUND LEXMARK INTERNATIONAL, INC. (US) 1999-11-04 WO disclosed
US-5342719-A Imaging members having a hydroxy aryl amine charge transport layer XEROX CORPORATION (US) 1994-08-30 US disclosed