Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144890 | 0.98 | RAB9A (0.49) | RAB9AALDH1A1GFERPSMD14CYP3A4 | |
| SCHEMBL5146739 | 0.96 | ALDH1A1 (0.48) | RAB9AALDH1A1GFERPSMD14CYP3A4 | |
| SCHEMBL5146728 | 0.92 | ALDH1A1 (0.50) | RAB9AALDH1A1GFERPSMD14CYP3A4 | |
| SCHEMBL11302817 | 0.81 | RAB9A (0.40) | RAB9AALDH1A1GFERMEN1KMT2A | |
| SCHEMBL22313470 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1KMT2AKDM4ENOS3 | |
| SCHEMBL23691297 | 0.79 | HTT (0.43) | ALDH1A1TDP1L3MBTL1KMT2AKDM4E | |
| SCHEMBL8121053 | 0.77 | SLC18A3 (0.60) | ALDH1A1CYP3A4TSHRMAPK1RECQL | |
| SCHEMBL23710686 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4ENOS3NOS1NOS2 | |
| SCHEMBL10052123 | 0.75 | SLC18A3 (0.58) | ALDH1A1TSHRTDP1L3MBTL1KMT2A | |
| SCHEMBL20210323 | 0.75 | SLC18A3 (0.46) | ALDH1A1TDP1KMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNA5, KCNH1, KCNK5 | RAB9A 2177/4885ALDH1A1 888/4885GFER 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.