Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512914 | 0.89 | CYP1A2 (0.38) | LMNACYP2D6MAPK1CYP2C9HTT | |
| SCHEMBL11781192 | 0.89 | LMNA (0.40) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL649844 | 0.82 | CHRM1 (0.40) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL8505186 | 0.79 | LMNA (0.55) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL23174612 | 0.79 | BBOX1 (0.50) | CYP2C19TERTBBOX1 | |
| SCHEMBL11781198 | 0.77 | CYP1A2 (0.41) | LMNACYP2D6MAPK1CYP2C9TSHR | |
| Iodide SCHEMBL4254403 | 0.77 | BBOX1 (0.48) | CYP2C19TERTBBOX1 | |
| SCHEMBL15876799 | 0.77 | ALDH1A1 (0.42) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL8864154 | 0.76 | LMNA (0.42) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL23754813 | 0.75 | LMNA (0.58) | LMNACYP2D6CYP3A4MAPK1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10459358-B2 | Method for producing a toner | ZEON CORPORATION (JP) | 2019-10-29 | — | — | US | disclosed |
| US-10372054-B2 | Toner | ZEON CORPORATION (JP) | 2019-08-06 | — | — | US | disclosed |
| US-20180307149-A1 | METHOD FOR PRODUCING A TONER | ZEON CORPORATION (JP) | 2018-10-25 | — | — | US | disclosed |
| US-10012917-B2 | Toner | ZEON CORPORATION (JP) | 2018-07-03 | — | — | US | disclosed |
| US-20180136574-A1 | TONER | ZEON CORPORATION (JP) | 2018-05-17 | — | — | US | disclosed |
| US-9904192-B2 | Toner | ZEON CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20170248856-A1 | TONER | ZEON CORPORATION (JP) | 2017-08-31 | — | — | US | disclosed |
| US-20160246196-A1 | TONER | ZEON CORPORATION (JP) | 2016-08-25 | — | — | US | disclosed |
| US-20160054671-A1 | TONER | ZEON CORPORATION (JP) | 2016-02-25 | — | — | US | disclosed |
| US-20060172209-A1 | Toner for developing electrostatic image and method of forming image using the same | ZEON CORPORATION | 2006-08-03 | — | — | US | disclosed |