Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840071 | 0.83 | — | — | |
| Sulfuric Acid SCHEMBL28557396 | 0.77 | TP53 (0.42) | TP53CA1CA2CA9LMNA | |
| SCHEMBL1343067 | 0.77 | — | — | |
| Sulfuric Acid SCHEMBL11155340 | 0.75 | ALDH1A1 (0.62) | TP53MAPK1CA1CA2CA9 | |
| Sulfuric Acid SCHEMBL28238705 | 0.75 | TP53 (0.41) | TP53CA1CA2CA9LMNA | |
| Sulfuric Acid SCHEMBL2127327 | 0.75 | TP53 (0.41) | TP53CA1CA2CA9LMNA | |
| Sulfuric Acid SCHEMBL11327555 | 0.75 | ALDH1A1 (0.62) | TP53MAPK1CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL16470724 | 0.73 | CA1 (0.32) | CA1CA2CA9 | |
| Sulfuric Acid SCHEMBL8088341 | 0.72 | TP53 (0.39) | TP53CA1CA2CA9LMNA | |
| Sulfuric Acid SCHEMBL10863257 | 0.72 | ALDH1A1 (0.59) | TP53MAPK1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309669-B1 | MECHANICALLY STABLE, LIQUID FORMULATION WASHING, RINSING OR CLEANING AGENT DOSES | HENKEL KGAA (DE) | 2006-10-04 | — | — | EP | disclosed |
| US-20040063598-A1 | Mechanically stable, liquid formulation washing, rinsing or cleaning agent doses | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-04-01 | — | — | US | disclosed |
| EP-1309669-A2 | MECHANICALLY STABLE, LIQUID FORMULATION WASHING, RINSING OR CLEANING AGENT DOSES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002048309-A1 | WASHING, RINSING OR CLEANING AGENT PORTIONS WITH TRANSPARENT SHELL | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002014460-A2 | MECHANICALLY STABLE, LIQUID FORMULATION WASHING, RINSING OR CLEANING AGENT DOSES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-21 | — | — | WO | disclosed |