Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335898 | 0.98 | OPRM1 (0.39) | DNM1THRBTSHROPRM1MEN1 | |
| SCHEMBL27278429 | 0.91 | OPRM1 (0.42) | DNM1THRBTSHROPRM1MEN1 | |
| SCHEMBL22442052 | 0.91 | OPRM1 (0.42) | DNM1THRBTSHROPRM1MEN1 | |
| SCHEMBL29253592 | 0.91 | OPRM1 (0.42) | DNM1THRBTSHROPRM1MEN1 | |
| SCHEMBL9149362 | 0.86 | LMNA (0.40) | DNM1OPRM1USP2SPHK1 | |
| SCHEMBL30589896 | 0.85 | LMNA (0.43) | CA1CA2CA9 | |
| SCHEMBL1067348 | 0.82 | THRB (0.57) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL3826183 | 0.82 | THRB (0.57) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL21218973 | 0.82 | THRB (0.57) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL2119344 | 0.82 | THRB (0.57) | THRBTSHRMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087705-B2 | Process for the monoalkylation of dihydroxy aromatic compounds | GENERAL ELECTRIC COMPANY (US) | 2006-08-08 | — | — | US | claimed |