Benzene

Benzene

SCHEMBL5665396

CCCCNS(=O)(=O)O.c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.56
CA12 O43570 5/20 0.56
CA1 P00915 4/20 0.56
CA14 Q9ULX7 3/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 3/20 0.49
PPARA Q07869 2/20 0.48
EPHX1 P07099 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 3/20 0.42
RECQL P46063 1/20 0.42
TSHR P16473 1/20 0.42
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177560 0.93
SCHEMBL27900603 0.91 CA2 (0.61) CA2CA12CA1CA14CA7
SCHEMBL27183344 0.91 CA2 (0.61) CA2CA12CA1CA14CA7
Hydrochloric Acid SCHEMBL11233885 0.91 CA2 (0.61) CA2CA12CA1CA14CA7
Fluoride SCHEMBL11230772 0.91 CA2 (0.61) CA2CA12CA1CA14CA7
Ammonia Solution, Strong SCHEMBL28922502 0.91 CA2 (0.61) CA2CA12CA1CA14CA7
SCHEMBL1076805 0.88 CA2 (0.61) CA2CA12CA1CA14CA7
SCHEMBL1704122 0.86 CA2 (0.65) CA2CA12CA1CA14CA7
SCHEMBL1728201 0.86 CA2 (0.65) CA2CA12CA1CA14CA7
SCHEMBL7757406 0.86 CA2 (0.65) CA2CA12CA1CA14CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6995273-B2 1H-pyrazolo[1,5-b]-1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-02-07 US disclosed
EP-1162504-B1 Coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2004-02-18 EP disclosed
US-20040002607-A1 1H-pyrazolo[1,5-b] -1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2004-01-01 US disclosed
US-6544724-B2 A pyrazolotriazole coupler having a specific structure including an amide linkage; improves solubility of coupler, light-fastness of dye FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-20020018973-A1 Coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2002-02-14 US disclosed
EP-1162504-A2 Coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2001-12-12 EP disclosed
EP-0333012-B1 Light-sensitive photopolymerisable printing plate BASF AG (DE) 1993-10-20 EP disclosed
EP-0248395-B1 PHOTOSENSITIVE REGISTRATION ELEMENT BASF Aktiengesellschaft (DE) 1991-06-05 EP disclosed
EP-0248395-A2 Photosensitive registration element BASF Aktiengesellschaft (DE) 1987-12-09 EP disclosed
EP-0243595-A2 Impact-resistant polyamide mouldings HÜLS AKTIENGESELLSCHAFT (DE) 1987-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020018973-A1 Coupler and silver halide color photographic light-sensitive material CBR1, CBR3, GRHPR CA2 344/4885CA12 136/4885CA1 864/4885
US-20040002607-A1 1H-pyrazolo[1,5-b] -1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material CBR3, CBR1, PPOX CA2 688/4885CA12 1513/4885CA1 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.