Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943316 | 0.76 | TGM2 (0.44) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28717475 | 0.74 | TGM2 (0.48) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10408489 | 0.70 | MDM2 (0.47) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9248562 | 0.70 | MDM2 (0.47) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17183746 | 0.70 | NPC1 (0.54) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23886140 | 0.70 | CNR1 (0.51) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3187688 | 0.70 | CPA1 (0.44) | CYP2C19TSHR | |
| SCHEMBL9357443 | 0.69 | MDM2 (0.46) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17183649 | 0.68 | MTNR1A (0.48) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19368239 | 0.68 | KCNA3 (0.53) | TGM2ALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320553-A4 | NOVEL POLYMER COMPOUNDS | PHAIRSON MEDICAL INC (GB) | 2006-03-15 | — | — | EP | disclosed |
| EP-1320553-A1 | NOVEL POLYMER COMPOUNDS | Phairson Medical, Inc. (GB) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002016443-A1 | NOVEL POLYMER COMPOUNDS | PHAIRSON MEDICAL INC. (GB) | 2002-02-28 | — | — | WO | disclosed |