SCHEMBL5666308

SCHEMBL5666308

CCCC=COc1ccc(N)cc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.51
MAPT P10636 6/20 0.51
ALDH1A1 P00352 6/20 0.51
KDM4E B2RXH2 5/20 0.51
HTT P42858 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
USP2 O75604 3/20 0.51
CASP1 P29466 2/20 0.51
TP53 P04637 1/20 0.51
POLB P06746 1/20 0.51
CASP7 P55210 1/20 0.51
ATM Q13315 1/20 0.51
TSHR P16473 2/20 0.36
LMNA P02545 2/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
PRKCI P41743 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28720362 0.72 TSHR (0.35) GAAMAPTALDH1A1KDM4EHTT
Hydrochloric Acid SCHEMBL18035235 0.72 ALDH1A1 (0.44) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL26015071 0.70 TLR8 (0.50) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL31756883 0.69 MAPT (0.96) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL394963 0.69 MAPT (0.96) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL5492231 0.69 MAPT (0.96) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL28459787 0.69 ALDH1A1 (0.44) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL28854577 0.69 ALDH1A1 (0.44) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL30678626 0.69 MAPT (0.69) GAAMAPTALDH1A1KDM4EHTT
SCHEMBL213433 0.69 MAPT (0.69) GAAMAPTALDH1A1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155353-B1 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS ELSICON INC (US) 2006-10-04 EP disclosed
US-6991834-B1 Materials for inducing alignment of liquid crystals and liquid crystal optical elements ELSICON, INC. (US) 2006-01-31 US disclosed
EP-1155353-A4 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS ELSICON INC (US) 2003-04-23 EP disclosed
US-6491988-B1 POLYAMIC ACID, POLYAMIDE ESTER AND POLYIMIDES; ANISOTROPICALLY ABSORBING; EXPOSING LAYER TO POLARIZED LIGHT; CROSSLINKING DIAMINES HAVING SIDE CHAINS OF C3-C22 LINEAR AND BRANCHED AND PARTIALLY FLUORINATED HYDROCARBONSCHAINS ELSICON, INC. 2002-12-10 US disclosed
EP-1155353-A1 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS Elsicon Inc. (US) 2001-11-21 EP disclosed
US-6313348-B1 LIQUID CRYSTAL GIBBONS WAYNE M (US) 2001-11-06 US disclosed
US-6103322-A POLYAMIC ACID ELSICON INC. (US) 2000-08-15 US disclosed
WO-2000039633-A1 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS ELSICON, INC. (US) 2000-07-06 WO disclosed