SCHEMBL394963

SCHEMBL394963

CCCOc1ccc(N)cc1N

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.96
KDM4E B2RXH2 2/20 0.96
GAA P10253 2/20 0.96
USP2 O75604 2/20 0.96
MEN1 O00255 1/20 0.96
ALDH1A1 P00352 1/20 0.96
TP53 P04637 1/20 0.96
POLB P06746 1/20 0.96
CASP1 P29466 1/20 0.96
HTT P42858 1/20 0.96
CASP7 P55210 1/20 0.96
KMT2A Q03164 1/20 0.96
ATM Q13315 1/20 0.96
CYP1A2 P05177 3/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2D6 P10635 2/20 0.48
SCN1A P35498 2/20 0.48
SCN2A Q99250 2/20 0.48
SCN3A Q9NY46 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5492231 1.00 MAPT (0.96) MAPTKDM4EGAAUSP2MEN1
SCHEMBL31756883 1.00 MAPT (0.96) MAPTKDM4EGAAUSP2MEN1
Hydrochloric Acid SCHEMBL29282743 0.98 GAA (1.00) MAPTKDM4EGAAUSP2MEN1
Hydrochloric Acid SCHEMBL27515267 0.98 GAA (1.00) MAPTKDM4EGAAUSP2MEN1
SCHEMBL29761215 0.90 KDM4E (0.79) MAPTKDM4EGAAUSP2MEN1
SCHEMBL10876363 0.90 KDM4E (0.79) MAPTKDM4EGAAUSP2MEN1
Hydrochloric Acid SCHEMBL15018737 0.89 GAA (0.83) MAPTKDM4EGAAUSP2MEN1
SCHEMBL27863947 0.89 MAPT (0.77) MAPTKDM4EGAAUSP2MEN1
SCHEMBL8099817 0.87 GAA (0.74) MAPTKDM4EGAAUSP2MEN1
SCHEMBL23014013 0.87 MAPT (0.74) MAPTKDM4EGAAUSP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119370-A Composition comprising an oxidation dye and a direct dye 花王株式会社 2024-05-31 CN claimed
CN-118043024-A Solid composition for dyeing keratin 花王株式会社 2024-05-14 CN claimed
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
CN-112089633-A Oxidation dyeing method 莱雅公司 2020-12-18 CN claimed
EP-3687978-A1 PARA-PHENYLENEDIAMINE BASES WITH CATIONIC HETEROCYCLES, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES L'Oreal (FR) 2020-08-05 EP claimed
EP-3687970-A1 PARA-PHENYLENEDIAMINE BASES WITH AN ALIPHATIC CHAINE AND TRIALKYL AMMONIUM GROUP, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES L'Oreal (FR) 2020-08-05 EP claimed
CN-111094249-A P-phenylenediamine bases having cationic heterocycles and their use for the oxidation dyeing of keratin fibers 莱雅公司 2020-05-01 CN claimed
EP-1453477-B1 DEVELOPER-COUPLER COMBINATION CONTAINING 2,4-DICHLORO-3-AMINOPHENOL HENKEL KGAA (DE) 2007-10-17 EP claimed
WO-2007097928-A2 HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-08-30 WO claimed
EP-1820488-A2 Hair colouring compositions The Procter and Gamble Company (US) 2007-08-22 EP claimed
US-20070186357-A1 Hair colouring compositions THE PROCTER & GAMBLE COMPANY 2007-08-16 US claimed
CN-1861562-A Process of producing nitrobenzether aminobenzether amidobenzether from chlorobenzene JIASEN CHEMICAL INDUSTRY CO LT (CN) 2006-11-15 CN claimed
US-20060156478-A1 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color L'OREAL S.A. (FR) 2006-07-20 US claimed
EP-1674075-A1 Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
EP-1674074-A1 Colored hair treating process with a composition comprising a specific non ionic and/or an amphoteric and/or a mild anionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
CN-1200682-C Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2005-05-11 CN claimed
CN-1278427-A Keratin-fiber oxidation dyeing composition and dyeing method using same OREAL (FR) 2001-01-03 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070186357-A1 Hair colouring compositions COX5A, COXFA4L2, COX5B MAPT 270/4885KDM4E 1337/4885GAA 2014/4885
US-20060156478-A1 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color KRT18, DSG1, DSP MAPT 998/4885KDM4E 624/4885GAA 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.