Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144461 | 0.82 | PNMT (0.69) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| Trifluoroacetic Acid SCHEMBL382794 | 0.80 | ITGB3 (0.36) | ITGB3ITGA2BKDM1A | |
| Trifluoroacetic Acid SCHEMBL4782632 | 0.78 | PNMT (0.43) | PNMTKDM1A | |
| Trifluoroacetic Acid SCHEMBL5708755 | 0.77 | KDM1A (0.49) | KDM1A | |
| Trifluoroacetic Acid SCHEMBL4237731 | 0.76 | PNMT (0.55) | PNMTKDM1A | |
| Trifluoroacetic Acid SCHEMBL384591 | 0.75 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2CKDM1A | |
| Trifluoroacetic Acid SCHEMBL3875578 | 0.75 | CHRNB2 (0.39) | ITGB3ITGA2BKDM1A | |
| Trifluoroacetic Acid SCHEMBL383551 | 0.74 | NOTUM (0.47) | — | |
| Trifluoroacetic Acid SCHEMBL3883763 | 0.73 | KDM4E (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL31122204 | 0.73 | ACSL1 (0.40) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | PNMT 1964/4885ADRA2A 280/4885ADRA2B 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.