Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.33 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666240 | 0.89 | PTPN5 (0.37) | PTPN5MC4R | |
| SCHEMBL30776957 | 0.80 | PTPN5 (0.35) | PTPN5 | |
| SCHEMBL29175703 | 0.80 | PTPN5 (0.35) | PTPN5 | |
| SCHEMBL5834556 | 0.80 | KAT8 (0.41) | S1PR4S1PR1TRPV1PLK1S1PR5 | |
| SCHEMBL27466288 | 0.76 | NPC1 (0.39) | TRPV1PLK1EIF4A1 | |
| SCHEMBL29175702 | 0.74 | HSP90AA1 (0.35) | PTPN5 | |
| SCHEMBL2638154 | 0.73 | TRPV1 (0.38) | S1PR4S1PR1TRPV1PLK1S1PR5 | |
| SCHEMBL5873319 | 0.73 | TRPV1 (0.38) | S1PR4S1PR1TRPV1PLK1S1PR5 | |
| SCHEMBL27480898 | 0.72 | PLK1 (0.34) | S1PR4S1PR1TRPV1PLK1S1PR5 | |
| SCHEMBL13700441 | 0.72 | KDM4E (0.33) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175467-B1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | claimed |