SCHEMBL5667265

SCHEMBL5667265

Nc1cccc(-c2ccccc2C2(c3ccccc3-c3cccc(N)c3O)c3ccccc3-c3ccccc32)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
OPRK1 P41145 1/20 0.47
KMT2A Q03164 1/20 0.47
PDK2 Q15119 11/20 0.46
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
MMP2 P08253 1/20 0.38
ALOX15 P16050 2/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19326650 0.92 SMN1; SMN2 (0.47) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL5667139 0.83 MEN1 (0.56) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL30175420 0.82 ALDH1A1 (0.50) SMN1; SMN2MEN1LMNAKMT2APDK2
SCHEMBL565923 0.82 ALDH1A1 (0.50) SMN1; SMN2MEN1LMNAKMT2APDK2
SCHEMBL9348335 0.81 SMN1; SMN2 (0.52) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL109214 0.81 KMT2A (0.56) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL29580288 0.81 KMT2A (0.56) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL3782730 0.81 ALDH1A1 (0.65) SMN1; SMN2KDM4EMEN1KMT2APDK2
SCHEMBL8984563 0.78 ALOX15 (0.46) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL15505765 0.78 PDK2 (0.56) SMN1; SMN2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed