Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687851 | 0.84 | KMT2A (0.48) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| Iodide SCHEMBL6674629 | 0.82 | HTR2A (0.53) | OPRK1CHRM1HRH1LMNAHTR2A | |
| SCHEMBL2522817 | 0.81 | CHRM2 (0.68) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL614300 | 0.81 | CHRM2 (0.68) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL2528597 | 0.80 | CHRM2 (0.67) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL2528600 | 0.80 | CHRM2 (0.67) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL615546 | 0.80 | CHRM2 (0.67) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9756347 | 0.80 | KMT2A (0.43) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL615095 | 0.78 | MAPT (0.46) | OPRK1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9230552 | 0.77 | KMT2A (0.41) | OPRK1CHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419135-A4 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LAB LTD (IN) | 2006-01-11 | — | — | EP | disclosed |
| EP-1419135-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES, LTD. (IN) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003014060-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2003-02-20 | — | — | WO | disclosed |