Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.68 |
| ▸ | HRH1 | P35367 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.68 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | HRH2 | P25021 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.68 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522817 | 1.00 | CHRM2 (0.68) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Hydrochloric Acid SCHEMBL615546 | 0.99 | CHRM2 (0.67) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Bromide SCHEMBL2528600 | 0.99 | CHRM2 (0.67) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Bromide SCHEMBL2528597 | 0.99 | CHRM2 (0.67) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Fumaric Acid SCHEMBL1261697 | 0.91 | CHRM2 (0.61) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Fumaric Acid SCHEMBL1261695 | 0.91 | CHRM2 (0.61) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Cadaverine Tartrate SCHEMBL2528604 | 0.91 | CHRM2 (0.74) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| Cadaverine Tartrate SCHEMBL2528602 | 0.91 | CHRM2 (0.74) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| SCHEMBL9227827 | 0.91 | MAPT (0.55) | CHRM2CHRM1HRH1MAPTCHRM5 | |
| SCHEMBL9228278 | 0.90 | CHRM2 (0.53) | CHRM2CHRM1HRH1MAPTCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041235-A1 | PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2012-02-16 | — | — | US | claimed |
| US-8039672-B2 | Method of obtaining 3,3-diphenylpropylamines | INTERQUIM, S.A. (ES) | 2011-10-18 | — | — | US | claimed |
| US-20100286446-A1 | Method of Obtaining 3,3-Diphenylpropylamines | INTERQUIM, S.A. (ES) | 2010-11-11 | — | — | US | claimed |
| WO-2010092500-A2 | A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE | ALEMBIC LIMITED (IN) | 2010-08-19 | — | — | WO | claimed |
| WO-2010046801-A2 | A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE | ALEMBIC LIMITED (IN) | 2010-04-29 | — | — | WO | claimed |
| EP-1927585-A2 | METHOD OF OBTAINING 3,3-DIPHENYLPROPYLAMINES | Ragactives, S.L. (ES) | 2008-06-04 | — | — | EP | claimed |
| EP-1698615-B1 | METHOD OF OBTAINING TOLTERODINE | RAGACTIVES SL (ES) | 2007-10-31 | — | — | EP | claimed |
| EP-1419135-A4 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LAB LTD (IN) | 2006-01-11 | — | — | EP | claimed |
| EP-1603862-A1 | 3,3-DIARYLPROPYLAMINE DERIVATIVES AND PROCESSES FOR ISOLATION THEREOF | Ranbaxy Laboratories Limited (IN) | 2005-12-14 | — | — | EP | claimed |
| US-20040249211-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-09 | — | — | US | claimed |
| US-6822119-B1 | REACTING 3,4-DIHYDRO-6-METHYL-4-PHENYL-2H-BENZOPYRAN-2-ONE WITH DIMETHYL SULFATE USING PHASE TRANSFER CATALYST; DESTERIFICATION, REDUCTION, AMINATION, SULFONATION, DEPROTECTING, DECYCLIZATION, AND SALT FORMATION | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-23 | — | — | US | claimed |
| WO-2004078700-A1 | 3,3-DIARYLPROPYLAMINE DERIVATIVES AND PROCESSES FOR ISOLATION THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-16 | — | — | WO | claimed |
| EP-1419135-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES, LTD. (IN) | 2004-05-19 | — | — | EP | claimed |
| WO-2003014060-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2003-02-20 | — | — | WO | claimed |
| EP-2007459-B1 | INHALER | BOEHRINGER INGELHEIM INT (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-1927585-B1 | METHOD OF OBTAINING 3,3-DIPHENYLPROPYLAMINES | INTERQUIM SA (ES) | 2016-07-27 | — | — | EP | disclosed |
| US-9085509-B2 | Process for preparing fesoterodine | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2015-07-21 | — | — | US | disclosed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249211-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | ADRB3, ADRA1B, ADRA2B | CHRM2 162/4885CHRM1 788/4885HRH1 1750/4885 |
| US-20120041235-A1 | PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF | PAH, UGT1A7, MLN | CHRM2 617/4885CHRM1 978/4885HRH1 3353/4885 |
| US-20100286446-A1 | Method of Obtaining 3,3-Diphenylpropylamines | CHRM3, HRH4, ADRB3 | CHRM2 4/4885CHRM1 29/4885HRH1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.