Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 10/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226091 | 0.91 | GAA (0.42) | KMT2AGAAMEN1OPRD1OPRM1 | |
| SCHEMBL9756292 | 0.91 | ACHE (0.41) | GAALPAR1ALDH1A1L3MBTL1 | |
| SCHEMBL9756351 | 0.90 | KMT2A (0.43) | KMT2AGAAMEN1OPRD1OPRM1 | |
| SCHEMBL9230552 | 0.89 | KMT2A (0.41) | KMT2AGAAMEN1OPRD1OPRM1 | |
| SCHEMBL9227320 | 0.86 | MEN1 (0.54) | KMT2AGAAMEN1OPRD1OPRM1 | |
| SCHEMBL9228200 | 0.86 | LMNA (0.51) | KMT2AMEN1OPRD1OPRM1OPRK1 | |
| Iodide SCHEMBL6674629 | 0.84 | HTR2A (0.53) | KMT2AGAAMEN1OPRM1OPRK1 | |
| SCHEMBL3687851 | 0.83 | KMT2A (0.48) | KMT2AGAAMEN1OPRD1OPRM1 | |
| SCHEMBL9228916 | 0.81 | HRH1 (0.48) | KMT2AGAAMEN1OPRK1MAPT | |
| SCHEMBL5667487 | 0.80 | OPRK1 (0.45) | KMT2AGAAMEN1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325571-B1 | NEW AMINES, THEIR USE AND PREPARATION | Kabi Pharmacia AB (SE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | disclosed |