SCHEMBL5669448

SCHEMBL5669448

C#Cc1c(Oc2ccc(C(=O)O)cc2)cccc1Oc1ccc(C(=O)O)cc1.c1cc2cc-2c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.44
RXRA P19793 3/20 0.43
RXRB P28702 2/20 0.43
TTR P02766 2/20 0.43
KMO O15229 1/20 0.42
PARP15 Q460N3 1/20 0.41
PARP10 Q53GL7 1/20 0.41
RARA P10276 1/20 0.41
RARB P10826 1/20 0.41
RARG P13631 1/20 0.41
AKR1C3 P42330 1/20 0.41
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
DHODH Q02127 1/20 0.40
LPAR1 Q92633 1/20 0.40
LPAR5 Q9H1C0 1/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5669449 0.80 TTR (0.45) SRD5A2RXRARXRBTTRKMO
SCHEMBL21177728 0.78 FEN1 (0.56) SRD5A2RXRARXRBTTRKMO
SCHEMBL2746171 0.78 DHODH (0.44) TTRKMOAKR1C3DHODHLPAR1
SCHEMBL28253414 0.77 LPAR1 (0.52) SRD5A2TTRPARP15PARP10AKR1C3
SCHEMBL5668230 0.76 BCL2 (0.50) RXRARXRBTTRKMORARA
SCHEMBL30307445 0.75 KMO (0.47) SRD5A2RXRARXRBTTRKMO
SCHEMBL5042492 0.75 SRD5A2 (0.65) SRD5A2RXRARXRBKMOPARP15
SCHEMBL29963803 0.75 SRD5A2 (0.65) SRD5A2RXRARXRBKMOPARP15
SCHEMBL7706043 0.74 SRD5A2 (0.68) SRD5A2TTRPARP15PARP10LPAR1
SCHEMBL4201178 0.72 LPAR1 (0.57) SRD5A2TTRPARP15PARP10AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed