SCHEMBL5669449

SCHEMBL5669449

O=C(O)c1ccc(Oc2cccc(Oc3ccc(C(=O)O)cc3)c2C#Cc2cccc(-c3ccccc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.45
SRD5A2 P31213 3/20 0.44
RXRA P19793 2/20 0.44
RXRB P28702 2/20 0.44
KMO O15229 1/20 0.43
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
PKM P14618 1/20 0.41
AKR1C3 P42330 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
CASP1 P29466 1/20 0.41
LPAR1 Q92633 2/20 0.40
LPAR5 Q9H1C0 2/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667762 0.80 BCL2 (0.49) SRD5A2RXRARXRBKMOTRIM24
SCHEMBL5669448 0.80 SRD5A2 (0.44) TTRSRD5A2RXRARXRBKMO
SCHEMBL5667489 0.80 DHODH (0.42) TTRRXRARXRBKMOAKR1C3
SCHEMBL21177728 0.78 FEN1 (0.56) TTRSRD5A2RXRARXRBKMO
SCHEMBL30307445 0.75 KMO (0.47) TTRSRD5A2RXRARXRBKMO
SCHEMBL21178077 0.75 EGFR (0.64) TTRSRD5A2RXRARXRBEGFR
SCHEMBL7706043 0.74 SRD5A2 (0.68) TTRSRD5A2PKMLPAR1LPAR5
SCHEMBL5667719 0.74 KMO (0.41) TTRKMOLMNA
SCHEMBL5669133 0.74 HNF4A (0.50) KMO
SCHEMBL28253414 0.74 LPAR1 (0.52) TTRSRD5A2PKMAKR1C3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed