Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223054 | 0.87 | TET2 (0.37) | ALOX15HSD17B10ALDH1A1CYP2D6 | |
| SCHEMBL11126445 | 0.82 | ALOX15 (0.47) | ALOX15HSD17B10ALDH1A1CYP2D6LMNA | |
| SCHEMBL11241202 | 0.82 | ALOX15 (0.47) | ALOX15HSD17B10ALDH1A1CYP2D6LMNA | |
| SCHEMBL5077938 | 0.82 | F7 (0.50) | ALOX15HSD17B10ALDH1A1FNTAFNTB | |
| SCHEMBL2043776 | 0.80 | FAAH (0.45) | ALOX15HSD17B10FNTAFNTBTERT | |
| SCHEMBL5074700 | 0.80 | PPARG (0.53) | ALOX15HSD17B10ALDH1A1FNTAFNTB | |
| SCHEMBL449780 | 0.79 | TERT (0.56) | ALOX15HSD17B10FNTAFNTBTERT | |
| SCHEMBL447706 | 0.79 | TERT (0.56) | ALOX15HSD17B10FNTAFNTBTERT | |
| SCHEMBL446813 | 0.79 | TERT (0.56) | ALOX15HSD17B10FNTAFNTBTERT | |
| SCHEMBL355323 | 0.79 | TERT (0.56) | ALOX15HSD17B10FNTAFNTBTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7025954-B2 | Materials for reshaping of essentially rigid keratinaceous surfaces | ESSTECH, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| EP-1148862-A4 | MATERIALS AND METHODS FOR RESHAPING OF ESSENTIALLY KERATINACEOUS SURFACES | ESSCHEM INC (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20030215635-A1 | Materials for reshaping of essentially rigid keratinaceous surfaces | ESSTECH, INC. | 2003-11-20 | — | — | US | disclosed |
| EP-1148862-A1 | MATERIALS AND METHODS FOR RESHAPING OF ESSENTIALLY KERATINACEOUS SURFACES | Esschem, Inc. (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000045775-A1 | MATERIALS AND METHODS FOR RESHAPING OF ESSENTIALLY KERATINACEOUS SURFACES | ESSCHEM, INC. (US) | 2000-08-10 | — | — | WO | disclosed |
| US-6080389-A | Materials and methods for reshaping of essentially rigid keratinaceous surfaces | ESSCHEM, INC. (US) | 2000-06-27 | — | — | US | disclosed |