Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 20/20 | 0.41 |
| ▸ | RARG | P13631 | 20/20 | 0.41 |
| ▸ | RARA | P10276 | 17/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596588 | 0.89 | CYP3A4 (0.49) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1140980 | 0.89 | RARA (0.39) | RARBRARGRARACYP3A4 | |
| SCHEMBL6591025 | 0.81 | KMT2A (0.33) | RARBRARGRARACYP3A4 | |
| SCHEMBL6588869 | 0.81 | CYP3A4 (0.53) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6592969 | 0.80 | NPC1 (0.36) | RARBRARGRARACYP3A4 | |
| SCHEMBL6591282 | 0.79 | MAPT (0.34) | RARBRARGRARACYP3A4 | |
| SCHEMBL7800461 | 0.76 | RARB (0.61) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6587152 | 0.74 | RARB (0.56) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6589951 | 0.72 | RARA (0.64) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6594145 | 0.72 | RARB (0.60) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576089-A4 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA CELL LTD (IL) | 2007-02-14 | — | — | EP | claimed |
| JP-2005528088-A | — | — | 2005-09-22 | — | — | JP | claimed |
| EP-1576089-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | Gamida Cell Ltd. (IL) | 2005-09-21 | — | — | EP | claimed |
| WO-2003062369-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA-CELL LTD. (IL) | 2003-07-31 | — | — | WO | claimed |