Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 15/20 | 0.67 |
| ▸ | ABCC8 | Q09428 | 15/20 | 0.67 |
| ▸ | KCNJ11 | Q14654 | 15/20 | 0.67 |
| ▸ | KCNJ8 | Q15842 | 15/20 | 0.67 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608774 | 0.86 | ABCC9 (0.70) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4609784 | 0.82 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL5549859 | 0.82 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4608254 | 0.80 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4608257 | 0.80 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4608961 | 0.80 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4608827 | 0.75 | PDK1 (0.72) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4608829 | 0.75 | PDK1 (0.72) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4609128 | 0.74 | ABCC9 (0.66) | ABCC9ABCC8KCNJ11KCNJ8PDK1 | |
| SCHEMBL4609272 | 0.72 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730310-A2 | A FORMULATION FOR INCREASING ENDOGENOUS ADIPONECTIN AND LEPTIN PRODUCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-13 | — | — | EP | claimed |
| US-20050261362-A1 | Method of increasing endogenous adiponectin and leptin production | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-11-24 | — | — | US | claimed |
| WO-2005092040-A2 | A FORMULATION FOR INCREASING ENDOGENOUS ADIPONECTIN AND LEPTIN PRODUCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-10-06 | — | — | WO | claimed |