SCHEMBL5669758

SCHEMBL5669758

Sc1nnnn1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
ALDH1A1 P00352 2/20 0.61
LMNA P02545 1/20 0.61
TSHR P16473 1/20 0.58
POLB P06746 2/20 0.51
MEN1 O00255 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
NOTUM Q6P988 8/20 0.46
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7049708 0.85 POLB (0.64) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL8655762 0.80 ALDH1A1 (0.41) MAPTALDH1A1LMNATSHRMEN1
SCHEMBL5685523 0.79 MAPT (0.56) MAPTALDH1A1LMNAHTTNOTUM
SCHEMBL11166727 0.79 MAPT (0.61) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL11348738 0.79 ALDH1A1 (0.61) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL13297693 0.75 MAPT (0.41) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL25208715 0.75 ALDH1A1 (0.62) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL1249689 0.74 NOTUM (0.39) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL8659110 0.74 MAPK10 (0.57) MAPTALDH1A1LMNATSHRPOLB
SCHEMBL6278254 0.74 L3MBTL1 (0.45) MAPTALDH1A1LMNATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5124229-A Containing tertiary and secondary alkanolamines, mixture of 1-phenyl-1H-tetrazole-5-thiol and halogen derivative thereof AGFA-GEVAERT, N.V. (BE) 1992-06-23 US claimed
US-5063136-A Silver complex diffusion transfer reversal process using an mixture of an alkanolamine and two 1-(halogen-substituted phenyl)-1H-tetrazole-5-thiol derivatives; low carbon dioxide absorption AGFA-GEVAERT, N.V. (BE) 1991-11-05 US claimed
EP-0397927-A1 Processing liquid suitable for use in the silver complex diffusion transfer processing AGFA-GEVAERT N.V. (BE) 1990-11-22 EP claimed
EP-0397925-A1 Processing liquid for use in DTR-photography AGFA-GEVAERT N.V. (BE) 1990-11-22 EP claimed
US-9753188-B2 Inorganic-organic hybrid material, optical material using the same, and inorganic-organic composite composition NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) 2017-09-05 US disclosed
EP-2586826-B1 INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION NIPPON KASEI CHEM (JP) 2015-11-25 EP disclosed
US-20140316033-A1 INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING THE SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) 2014-10-23 US disclosed
US-8815388-B2 Inorganic-organic hybrid material, optical material using the same, and inorganic-organic composite composition NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) 2014-08-26 US disclosed
US-20130116362-A1 INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING THE SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2013-05-09 US disclosed
EP-2586826-A1 INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION Nippon Kasei Chemical Company Limited (JP) 2013-05-01 EP disclosed
WO-2007099108-A1 METHOD FOR MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2007-09-07 WO disclosed
EP-1535499-B1 PROCESS FOR PREPARING A SUBSTANTIALLY TRANSPARENT CONDUCTIVE LAYER CONFIGURATION AGFA GEVAERT (BE) 2006-12-13 EP disclosed
US-5063136-A Silver complex diffusion transfer reversal process using an mixture of an alkanolamine and two 1-(halogen-substituted phenyl)-1H-tetrazole-5-thiol derivatives; low carbon dioxide absorption AGFA-GEVAERT, N.V. (BE) 1991-11-05 US disclosed
EP-0397927-A1 Processing liquid suitable for use in the silver complex diffusion transfer processing AGFA-GEVAERT N.V. (BE) 1990-11-22 EP disclosed
EP-0397925-A1 Processing liquid for use in DTR-photography AGFA-GEVAERT N.V. (BE) 1990-11-22 EP disclosed
EP-0398435-A1 Liquid for DTR-photography AGFA-GEVAERT N.V. (BE) 1990-11-22 EP disclosed
EP-0397926-A1 Processing liquid for use in silver halide photography AGFA-GEVAERT N.V. (BE) 1990-11-22 EP disclosed
EP-0026519-B1 PHOTOGRAPHIC SILVER HALIDE EMULSION MATERIAL CONTAINING AN ANTIFOGGANT PRECURSOR AGFA-GEVAERT N.V. (BE) 1983-08-17 EP disclosed
US-4307175-A Photographic silver halide emulsion material containing an antifoggant precursor AGFA-GEVAERT, N.V. (BE) 1981-12-22 US disclosed
EP-0026519-A1 Photographic silver halide emulsion material containing an antifoggant precursor AGFA-GEVAERT N.V. (BE) 1981-04-08 EP disclosed