Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858362 | 0.79 | GAA (0.43) | CETPRXRARXRBRXRG | |
| SCHEMBL5179716 | 0.68 | CETP (0.47) | CETPSCN9A | |
| SCHEMBL5670438 | 0.67 | CETP (0.35) | CETP | |
| SCHEMBL16267445 | 0.66 | PTGS1 (0.40) | CETP | |
| SCHEMBL14730903 | 0.66 | PTGS1 (0.40) | CETP | |
| SCHEMBL5671027 | 0.66 | LMNA (0.40) | CETP | |
| SCHEMBL5672750 | 0.66 | CETP (0.45) | CETPPPARG | |
| SCHEMBL5181270 | 0.65 | SLC5A2 (0.35) | CETP | |
| SCHEMBL5670433 | 0.65 | CETP (0.47) | CETP | |
| SCHEMBL5671811 | 0.64 | KDM1A (0.44) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |