Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813279 | 0.81 | TSHR (0.40) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL21776979 | 0.81 | NOTUM (0.56) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL10222516 | 0.77 | TSHR (0.57) | TSHRALDH1A1SMN1; SMN2NOTUMAKR1C2 | |
| SCHEMBL4942021 | 0.77 | CYP1A2 (0.50) | TSHRALDH1A1CASP1SMN1; SMN2NOTUM | |
| SCHEMBL4339765 | 0.75 | ALDH1A1 (0.36) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL29886586 | 0.74 | TSHR (0.64) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL432644 | 0.74 | TSHR (0.64) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL29154613 | 0.74 | AKR1C2 (0.39) | TSHRALDH1A1TP53CASP1SMN1; SMN2 | |
| SCHEMBL9889139 | 0.74 | NOTUM (0.38) | NOTUMTDP1 | |
| SCHEMBL108571 | 0.74 | TSHR (0.52) | TSHRALDH1A1TP53CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820494-B | Nuclear receptor modulators | 艾伯维公司 | 2020-10-16 | — | — | CN | disclosed |
| US-20060210812-A1 | Insulating film and method of forming the same | JSR CORPORATION (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1679184-A1 | LAMINATE AND METHOD FOR FORMATION THEREOF, INSULATING FILM, SEMICONDUCTOR DEVICE, AND COMPOSITION FOR FORMING FILM | JSR Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |